Day: September 10, 2020

33100-27-5, 1,4,7,10,13-Pentaoxacyclopentadecane is a chiral-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: Crystals of compounds 1?3 were prepared by isothermal evaporation fromaqueous solutions at room temperature. The crystals of compound 1 weresynthesized by the reaction of 0.051 g (0.1 mmol) of UO2(NO3)2¡¤6H2O,0.040 g (0.22 mmol) of 12-crown-4, 0.280 g (2.0 mmol) of 40percent H2SeO4,and 2.001 g (111.2 mmol) of deionized distilled water. Compound 2:0.050 g (0.1 mmol) of uranyl nitrate, 0.046 g (0.21 mmol) of 15-crown-5,0.282 g (2.0 mmol) of selenic acid, and 2.012 g (111.7 mmol) of deionizeddistilled water. Compound 3: 0.050 g (0.1 mmol) of uranyl nitrate, 0.046 g(0.21 mmol) of 15-crown-5, 0.282 g (2.0 mmol) of selenic acid, and 2.012 g(111.7 mmol) of deionized distilled water (note: the bulk of crystals herebelongs to compound 2). Homogeneous liquid solutions were left in awatch glass. Yellowish-green flattened crystals formed within 2 weeks., 33100-27-5

As the paragraph descriping shows that 33100-27-5 is playing an increasingly important role.

Reference£º
Article; Gurzhiy, Vladislav V.; Tyumentseva, Olga S.; Tyshchenko, Darya V.; Krivovichev, Sergey V.; Tananaev, Ivan G.; Mendeleev Communications; vol. 26; 4; (2016); p. 309 – 311;,
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1,3-Bis(2,6-diisopropylphenyl)imidazolium chloride, cas is 250285-32-6, it is a common heterocyclic compound, the chiral-catalyst compound, its synthesis route is as follows.,250285-32-6

General procedure: 4.23.1. [1,3-Bis(2,6-di-iso-propylphenyl)imidazol-2-ylidene] copper(I) chloride, (IPr)CuCl [23] An oven-dried Schlenk flask containing 1,3-bis(2,6-di-iso-propylphenyl) imidazolium chloride (849.0 mg, 2.00 mmol), CuCl (198.0 mg, 2.00 mmol), NaOt-Bu (192.0 mg, 2.00 mmol) was evacuated and refilled with argon three times. THF (10 mL) were added to this Schlenk flask. The resulting suspension was stirred at room temperature for 4 h. Then, it was filtered through Celite in glovebox. Yield: 81%; white powder; IR (KBr): 3160, 3137, 3070, 2968, 2926, 2869, 1963, 1577, 1469, 1456, 1405, 1383, 1327, 1114, 1104, 1212, 1058, 937, 946, 809, 765, 742, 699 cm 1; 1H NMR (400 MHz, CDCl3): d = 7.48 (t, J = 8.0 Hz, 2H), 7.29 (d, J = 7.6 Hz, 4H), 7.11 (s, 2H), 2.53-2.60 (m, 4H), 1.30 (d, J = 12 Hz, 12H), 1.22 (d, J = 6.8 Hz, 12H); 13C NMR (100 MHz, CDCl3): d = 180.6, 145.6, 134.4, 130.6, 124.2, 123.2, 28.8, 24.9, 23.9.

As the rapid development of chemical substances, we look forward to future research findings about 250285-32-6

Reference£º
Article; Wu, Shaoxiang; Guo, Jiyi; Sohail, Muhammad; Cao, Chengyao; Chen, Fu-Xue; Journal of Fluorine Chemistry; vol. 148; (2013); p. 19 – 29;,
Chiral Catalysts
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(S)-2-(Methoxymethyl)pyrrolidine, cas is 63126-47-6, it is a common heterocyclic compound, the chiral-catalyst compound, its synthesis route is as follows.,63126-47-6

General procedure: A mixture of aldehyde (1.97 mmol), amine (1.97 mmol), acetylene (2.95 mmol), and thecorresponding supported Au catalyst (1percent wt, 60 mg, 0.002 mmol) was heated at 60 ¡ãC for 8 h,after which time the solution was cooled and the catalyst was removed by filtration. The filtrate wasevaporated under reduced pressure to afford propargylamine 5. Yields were determined by integration of the 1H-NMR spectra of the crude reaction mixtures. After separation and washing with n-pentane,the catalyst was reused intact for the next reaction without any further pre-treatment.

As the rapid development of chemical substances, we look forward to future research findings about 63126-47-6

Reference£º
Article; Soengas, Raquel; Navarro, Yolanda; Iglesias, Maria Jose; Lopez-Ortiz, Fernando; Molecules; vol. 23; 11; (2018);,
Chiral Catalysts
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1,3-Dimesityl-1H-imidazol-3-ium chloride, cas is 141556-45-8, it is a common heterocyclic compound, the chiral-catalyst compound, its synthesis route is as follows.,141556-45-8

To anhydrous 1,4-dioxane (20 mL), [Pd(acac)2] (1 g, 3.3 mmol,1 equiv) and IMes*HCl (1.43 g, 3.7 mmol, 1.1 equiv) were added. The mixture was refluxed for 24 h. After the reaction, solvent was evaporated under vacuum. Diethyl ether was then added and stirred until no more solid was dissolved. The solution was filtered and diethyl ether was removed under vacuum. Yellow powder was washed with n-pentane and dried under vacuum. Yellow solids, yield:85%, 1H NMR (399.78 MHz, CDCl3) delta 7.08-6.94 (br,6H), 5.1 (s, 1H), 2.47-2.02 (br, 18H), 1.84-1.73 (6H), 13CNMR (100.53 MHz, CDCl3) delta 187.21, 183.16, 153.93,139.29, 137.60, 136.35, 135.01, 129.76, 128.90, 123.8,122.57, 99.68, 27.17, 25.61, 21.29, 18.93, 17.85.Synthesis of (IMes)Pd(tmhd)Cl. Yellow solids, yield:76%, 1H NMR (399.78 MHz, CDCl3) delta 7.09-6.96 (6H),5.50 (s, 1H), 2.40-2.31 (12H), 2.21-2.16 (6H), 1.04-0.95(18H), 13C NMR (100.53 MHz, CDCl3) delta 139.08, 136.64,135.40, 130.00, 128.74, 124.04, 90.65, 41.15-40.64, 29.07,28.51, 21.25, 18.99.

As the rapid development of chemical substances, we look forward to future research findings about 141556-45-8

Reference£º
Article; Lee, Dong Jin; Kim, Myungwoong; Kim, Chan Kyung; Lee, Ik Mo; Bulletin of the Korean Chemical Society; vol. 40; 7; (2019); p. 710 – 718;,
Chiral Catalysts
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141556-45-8, 1,3-Dimesityl-1H-imidazol-3-ium chloride is a chiral-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: 0.340 g (1.00 mmol) of 1,3-bis(2,4,6-trimethylphenyl)imidazolium chloride was deprotonated by the addition of n-BuLi (1.00 mmol) in THF at -40C. The reaction mixture was allowed to stir for 30 min after which 0.390 g dimanganese decacarbonyl (1.00 mmol) was added. The reaction mixture turned a deep orange colour after the introduction of the metal complex and the reaction mixture was allowed to slowly warm up to room temperature. The solvent was removed in vacuo and purified via silica gel chromatography by eluting first with hexane and secondly with a hexane-DCM 1:1 mixture.

141556-45-8, As the paragraph descriping shows that 141556-45-8 is playing an increasingly important role.

Reference£º
Article; Fraser, Roan; van Sittert, Cornelia G.C.E.; van Rooyen, Petrus H.; Landman, Marile; Journal of Organometallic Chemistry; vol. 835; (2017); p. 60 – 69;,
Chiral Catalysts
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With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.22795-99-9,(S)-(1-Ethylpyrrolidin-2-yl)methanamine,as a common compound, the synthetic route is as follows.

In a glovebox under argon, to chamber 1 of two- chamber system S2 was added Pd(dba)2 (19.9 mg, 0.0347 mmol), PPh3 (18.2 mg, 0.0693 mmol), 4,6-dichloro-2-iodo-3-methoxyphenol 37 (221 mg, 0.693 mmol), THF (3 ml_), (S)-(l-ethylpyrrolidin-2-yl)methanamine (193 muIota_, 1.39 mmol), TEA (194 muIota_, 1.39 mmol). The chamber was sealed with a screwcap fitted with a Teflon.(R). seal. In a glovebox under argon, to chamber 2 of two-chamber system S2 was added Mo(CO)6 (183 mg, 0.693 mmol), THF (3 ml_) and pyridine (280 muIota_, 3.47 mmol) in that order. The chamber was sealed with a screwcap fitted with a Teflon.(R). seal. The loaded two-chamber system was heated to 70 ¡ãC for 19 hours. The crude reaction mixture was evaporated on silica gel and the title compound 38 was obtained after flash chromatography (5percent MeOH in CH2CI2 as eluent) as brown oil (153.7 mg, 0.443 mmol, 64percent from 37)., 22795-99-9

22795-99-9 (S)-(1-Ethylpyrrolidin-2-yl)methanamine 643457, achiral-catalyst compound, is more and more widely used in various fields.

Reference£º
Patent; AARHUS UNIVERSITET; SKRYDSTRUP, Troels; LINDHARDT, Anders Thyboe; HERMANGE, Philippe; TAANING, Rolf Hejle; FRIIS, Stig Duering; WO2012/79583; (2012); A1;,
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94-91-7,94-91-7, N,N’-Bis(salicylidene)-1,2-propanediamine is a chiral-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: A mixture of diimine (10 mmol) and amidophosphite(10 mmol) in acetonitrile (20 mL) was refluxed for 1 h. Thesolvent was removed by distillation; the residue was dissolved inamethylene chloride-hexane mixture. The precipitated productwas recrystallized from benzene.

As the paragraph descriping shows that 94-91-7 is playing an increasingly important role.

Reference£º
Article; Pudovik, Michael A.; Kibardina, Ludmila K.; Terent’eva, Svetlana A.; Dobrynin, Alexey B.; Trifonov, Alexey V.; Burilov, Alexander R.; Phosphorus, Sulfur and Silicon and the Related Elements; vol. 194; 9; (2019); p. 861 – 865;,
Chiral Catalysts
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With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.250285-32-6,1,3-Bis(2,6-diisopropylphenyl)imidazolium chloride,as a common compound, the synthetic route is as follows.

Tris [4- (pyridin-4-yl) phenyl] amine compound (47.6 mg, 0.10 mmol)1,3-bis (2,6-diisopropylphenyl) imidazolium chloride (IPr.HCl) (127.5 mg, 0.30 mmol),PdCl2 (53.2 mg, 0.30 mmol)And potassium carbonate (41.5 mg, 0.30 mmol) were added to a 25 mL single neck flask,Tetrahydrofuran (5 mL) was then added,The reaction was stirred at 65 C for 16 h under argon atmosphere.Stop the reaction,Cool to room temperature,concentrate,Thin layer chromatography to give compound I,Yield 57%.

250285-32-6, As the paragraph descriping shows that 250285-32-6 is playing an increasingly important role.

Reference£º
Patent; Shangqiu Normal University; Wang Tao; Xu Kai; Liu Lantao; Zhao Wenxian; Liu Shuang; Li Feng; Meng Tuanjie; Xie Huanping; (12 pag.)CN105131044; (2017); B;,
Chiral Catalysts
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(S)-(1-Ethylpyrrolidin-2-yl)methanamine, cas is 22795-99-9, it is a common heterocyclic compound, the chiral-catalyst compound, its synthesis route is as follows.,22795-99-9

49 g of methyl 2-methoxy-5-sulfamoylbenzoate and(S)-1-ethyl-2-aminomethyltetrahydropyrrolidine 26.5gAdd to the reaction bottle,The reaction was carried out at 90 to 100 ¡ã C for 5 hours under nitrogen protection.The reaction was completed, cooled to 80 ¡ã C, 50 g of ethanol was added, and the mixture was stirred and refluxed for 10 minutes.Cool to 5 ¡ã C and stir for 2 hours, filter,It was washed with ethanol and dried at 65 ¡ãC.The yield was 93.8percent, and the purity was 99.2percent.

As the rapid development of chemical substances, we look forward to future research findings about 22795-99-9

Reference£º
Patent; Jiangsu Tianshili Diyi Pharmaceutical Co., Ltd.; Liu Jinping; Liu Wenzheng; Zhu Zhanyuan; Yang Guojun; (5 pag.)CN103804265; (2018); B;,
Chiral Catalysts
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Benzo-18-crown 6-Ether, cas is 14098-24-9, it is a common heterocyclic compound, the chiral-catalyst compound, its synthesis route is as follows.,14098-24-9

General procedure: 4.2.1. Method A. molecular clip 2 was obtained in 50% yield as described6b Method B. A mixture of bisether 8 (1 g, 2.65 mmol) and corresponding benzocrown ether (5.42 mmol) in PPA (30 g) was stirred vigorously at 80-85 for 30 min. A deep purple color was formed in 5 min. To the cooled reaction mixture was added water (150 mL) and product was extracted with CHCl3 (3¡Á50 mL). The organic layer was washed with water until neutral (?3¡Á50 mL) and subjected to azeotropic drying. The solvent was removed at reduced pressure and the residue was dissolved in a mixture of CHCl3/MeOH (50:1, 100 mL) and filtered through SiO2 (~30 mL). The solvent was removed at reduced pressure and the crude product was purified as described below. Method C. The procedure is similar to Method B, with exception that tetraol 9 (1.1 g, 2.65 mmol) was used instead bisether 8. Method D. A suspension of NaH (0.288 g, 12 mmol) in DMSO (26 mL) was heated with stirring at 70 for 30 min. The resulting mixture was cooled to room temperature and a solution of 11 (0.78 g, 2.65 mmol) in DMSO (40 mL) was added. Stirring was continued for 20 min and then solution of 10 (5.92 g, 5.83 mmol) in DMSO (40 mL) was added dropwise over 5 min and the resulting mixture was stirred at room temperature for 24 h. The mixture was poured into ice water (400 mL) and acidified with HCl to pH~2. The resulting solid was filtered off, washed with water (3¡Á50 mL). The crude product was purified as described below.

As the rapid development of chemical substances, we look forward to future research findings about 14098-24-9

Reference£º
Article; Bogaschenko, Tatiana Yu.; Lyapunov, Alexander Yu.; Kikot’, Leonid S.; Mazepa, Alexander V.; Botoshansky, Mark M.; Fonari, Marina S.; Kirichenko, Tatiana I.; Tetrahedron; vol. 68; 24; (2012); p. 4757 – 4764;,
Chiral Catalysts
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