One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, such as the rate of change in the concentration of reactants or products with time. 87-91-2, Name is (2R,3R)-Diethyl 2,3-dihydroxysuccinate, formurla is C8H14O6. In a document, author is Kelber, Julien B., introducing its new discovery. Computed Properties of C8H14O6.
Tuning the dihedral angle (DA) of axially chiral compounds can impact biological activity, catalyst efficiency, molecular motor performance, or chiroptical properties. Herein, we report gradual, controlled, and reversible changes in molecular conformation of a covalently linked binaphthyl moiety within a 3D polymeric network by application of a macroscopic stretching force. We managed direct observation of DA changes by measuring the circular dichroism signal of an optically pure BINOL-crosslinked elastomer network. Stretching the elastomer resulted in a widening of the DA between naphthyl rings when the BINOL was doubly grafted to the elastomer network; no effect was observed when a single naphthyl ring of the BINOL was grafted to the elastomer network. We have determined that ca. 170 % extension of the elastomers led to the transfer of a mechanical force to the BINOL moiety of 2.5 kcal mol(-1) angstrom(-1)(ca. 175 pN) in magnitude and results in the opening of the DA of BINOL up to 130 degrees.
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Reference:
Chiral Catalysts,
,Chiral catalysts – SlideShare