Formula: C6H15ClN2O. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: H-Leu-NH2.HCl, is researched, Molecular C6H15ClN2O, CAS is 10466-61-2, about Synthesis of amino acid-derived cyclic acyl amidines for use in β-strand peptidomimetics.
The acyl amidine represented by the 4,5-dihydro-2(3H)-pyrazinone ring system is isosteric to the vinylogous amide of the 1,2-dihydro-3(6H)-pyridinone, but its assembly from sep. amine and amide components enables ready incorporation of an amino acid side chain with correct regio- and stereochem. β-Strand peptidomimetics incorporating amino acid analogs have recently been shown to be potent, protease-resistant ligands to a PDZ protein-interaction domain. Two routes to the protected pyrazinone-containing dipeptide analog I are described. This dipeptide analog was finally incorporated into a peptidomimetics in two steps with good yields.
This compound(H-Leu-NH2.HCl)Formula: C6H15ClN2O was discussed at the molecular level, the effects of temperature and reaction time on the properties of the compound were discussed, and the optimum reaction conditions were selected.