Synthetic Route of 2133-34-8, Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 2133-34-8, Name is (S)-Azetidine-2-carboxylic acid, molecular formula is C4H7NO2. In a Article£¬once mentioned of 2133-34-8
Photochemical Preparation of Tricyclic Hydroxyketones by Transanular Cyclization of Bridged 4-Benzoylcyclohexanones
The bridged 4-benzoyl-cyclohexanones 3a-f were synthesized by alpha,alpha?-annelation of cyclic ketones. Irradiation of 3a-f revealed a strong dependence of the photochemical behaviour on the ring size and the introduction of a nitrogen atom. Ketones which are able to form 1,6-biradicals (3b,c,e) undergo unselective photolytic decomposition, whereas 3a,d,f afforded tricyclic hydroxyketones. The diastereoselectivity of ring closure is remarkably improved by introduction of a protected nitrogen atom (3d,f) in comparison to the carbocyclic diketone 3a. Moreover, the N protective group of 4-azatricyclo-[4.3.1.03,8]decan-7-one (7) could be removed affording the free hydroxy amino ketone 8 in good yields. An explanation of the diastereoselective cyclization of 3a and of the surprisingly low quantum yield of 3d was found by conformational analysis of the corresponding triplet biradicals.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 2133-34-8 is helpful to your research., Synthetic Route of 2133-34-8
Reference£º
Chiral Catalysts,
Chiral catalysts – SlideShare