The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. HPLC of Formula: C6H12ClNO, 168960-19-8, Name is ((1S,4R)-4-Aminocyclopent-2-en-1-yl)methanol hydrochloride, SMILES is OC[C@@H]1C=C[C@H](N)C1.[H]Cl, in an article , author is Luo, Weiwei, once mentioned of 168960-19-8.
A double divergent process has been developed for the reaction of alpha-enaminones with quinones through facile manipulation of catalyst and additive, leading to structurally completely different products. The two divergent processes, which involve formal aza- and oxo-[3 + 2] cycloaddition reactions, are mediated by chiral phosphoric acid and molecular sieves, respectively. While inclusion of phosphoric acid in the reaction switched the reaction pathway to favor the efficient formation of a wide range of N-substituted indoles, addition of 4 angstrom molecular sieves to the reaction switched the reaction pathway again, leading to enantioselective synthesis of 2,3-dihydrobenzofurans in excellent yields and enantioselectivities under mild conditions. Studies in this work suggest that the chiral phosphoric acid acts to lower the transition state energy and promote the formation of amide intermediate for the formal aza-[3 + 2] cycloaddition and the molecular sieves serve to facilitate proton transfer for oxo-[3 + 2] cycloaddition. The reactivity of alpha-enaminones is also disclosed in this work.
But sometimes, even after several years of basic chemistry education, it is not easy to form a clear picture on how they govern reactivity! 168960-19-8, you can contact me at any time and look forward to more communication. HPLC of Formula: C6H12ClNO.
Reference:
Chiral Catalysts,
,Chiral catalysts – SlideShare