Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 80657-57-4, Name is (S)-Methyl 3-hydroxy-2-methylpropanoate, molecular formula is C5H10O3, belongs to chiral-catalyst compound, is a common compound. In a patnet, author is Jung, Jungi, once mentioned the new application about 80657-57-4, Formula: C5H10O3.
It has been known that the enantioselectivity of the chiral Lewis base-catalyzed, SiCl4-promoted kinetic resolution of alpha,beta-dichloro cis-vinyl epoxide is highly influenced by the configuration of the distal beta-chlorine-bearing stereocenter. In this report, the precise nature of this unusual remote stereocontrol was investigated both experimentally and theoretically. Upon examination of a substrate that has an alkyl group in place of the beta-chlorine substituent, the spatial location of major catalyst-substrate interaction was determined. Subsequently, through computational analysis of transition states, the steric repulsion by the beta-substituents as well as the additional C-H/pi hydrogen bond by the alkyl substituent were proposed as the crucial stereo-determining factors. (C) 2020 Elsevier Ltd. All rights reserved.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 80657-57-4. The above is the message from the blog manager. Formula: C5H10O3.
Reference:
Chiral Catalysts,
,Chiral catalysts – SlideShare