Related Products of 17392-83-5, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 17392-83-5, Name is (R)-Methyl 2-hydroxypropanoate, SMILES is C[C@@H](O)C(OC)=O, belongs to chiral-catalyst compound. In a article, author is Hatano, Manabu, introduce new discover of the category.
A hydrogen bonding network in chiral Bronsted acid catalysts is important for the construction of a chiral cavity and the enhancement of catalytic activity. In this regard, we developed a highly enantioselective aza-Friedel-Crafts reaction of indoles and pyrroles with acyclic a-ketimino esters in the presence of a chiral C-1-symmetric BINOL-derived bis(phosphoric acid) catalyst. The desired alkylation products with chiral quaternary carbon centers were obtained in high yields with high enantioselectivities on up to a 1.2-g scale with 0.2 mol % catalyst loading. Interestingly, the absolute configurations of the products from indoles and pyrroles were opposite even with the use of the same chiral catalyst. Moreover, preliminary mechanistic considerations disclosed that a unique hydrogen bonding network with or without pi-pi interactions among the catalyst and substrates might partially play a pivotal role.
Related Products of 17392-83-5, The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 17392-83-5 is helpful to your research.
Reference:
Chiral Catalysts,
,Chiral catalysts – SlideShare