Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 57-48-7, Name is (3S,4R,5R)-1,3,4,5,6-Pentahydroxyhexan-2-one, molecular formula is C6H12O6, belongs to chiral-catalyst compound, is a common compound. In a patnet, author is Gernet, Aurelie, once mentioned the new application about 57-48-7, Recommanded Product: (3S,4R,5R)-1,3,4,5,6-Pentahydroxyhexan-2-one.
We herein report, a practical and efficient strategy for the synthesis of enantiomerically enriched 2-amino-1-arylethanols, a structural motif commonly encountered in the family of beta-adrenergic blockers or agonists, through a Lewis base-catalyzed SiCl4-mediated asymmetric Passerini-type reaction of isocyanides with aldehydes. The protocol features a simple one-pot, two-step procedure, the use of commercially available starting materials, a broad functional group tolerance, and high levels of selectivity up to 98.5:1.5 er. Application to the synthesis of the salbutamol acetate salt, a drug widely used as a bronchodilator to manage asthma and other chronic obstructive airway diseases is also reported.
We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 57-48-7. The above is the message from the blog manager. Recommanded Product: (3S,4R,5R)-1,3,4,5,6-Pentahydroxyhexan-2-one.
Reference:
Chiral Catalysts,
,Chiral catalysts – SlideShare