Final Thoughts on Chemistry for Dibenzo-18-crown-6

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The distribution of organic nonelectrolytes of various classes (hydrocarbons, halogenated hydrocarbons, and oxygen-, nitrogen-, sulfur-, and phosphorus-containing substances) and various structures (mono- and polyfunctional substances, isomers, and heterocyclic compounds) was systematically studied at 20 ± 1C in the n-octane-water extraction system characterized by a vanishingly small mutual solubility of phase components. The distribution constants of substances and the increments of the methylene and functional groups in the logarithms of distribution constants were calculated. The distribution constants of substances of various structures calculated with the use of increments and determined experimentally were compared. Based on an analysis of the results, the applicability limits of using the additivity rule for describing and predicting the distribution of substances in the specified system were formulated. The obtained data were shown to be useful for rapidly and correctly estimating the Gibbs energy of hydration and solvation of organic nonelectrolytes.

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Reference:
Chiral Catalysts,
Chiral catalysts – SlideShare