Extracurricular laboratory:new discovery of (1S,2S)-Cyclohexane-1,2-diamine

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Synthetic Route of 21436-03-3, Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, get their minds active, and encourage them to do something that doesn’t involve a screen. 21436-03-3, C6H14N2. A document type is Article, introducing its new discovery.

An efficient two-step synthesis of a wide range of 3-methylene-1,2- diazetidines has been developed through application of a Cu(I)-catalyzed 4-exo ring closure. The double bond of this new class of strained heterocycle can be functionalized in a stereocontrolled manner by using palladium-catalyzed Heck reactions. Moreover, chemoselective reduction of 3-alkylidene-1,2-diazetidines gives access to saturated 1,2-diazetidines and vicinal diamines.

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Reference:
Chiral Catalysts,
Chiral catalysts – SlideShare