Downstream synthetic route of 1,3-Bis(2,6-diisopropylphenyl)imidazolium chloride

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 1,3-Bis(2,6-diisopropylphenyl)imidazolium chloride, 250285-32-6

250285-32-6, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 1,3-Bis(2,6-diisopropylphenyl)imidazolium chloride, cas is 250285-32-6,the chiral-catalyst compound, it is a common compound, a new synthetic route is introduced below.

Under inert atmosphere, 1,3-bis-(2,6-diisopropylphenyl)imidazolium chloride (1.59 g,3.74 mmol, 1.00 equiv.) was dissolved in dichloromethane (170 mL) and silver(I) oxide (0.478 g,2.06 mmol, 1.10 equiv.) was added. The mixture was stirred at room temperature for 25 h and then iodine (1.04 g, 4.10 mmol, 1.10 equiv.) in dichloromethane (50 mL) was added slowly andstirred overnight. The mixture was deactivated by NaS2O3, the organic layer was separated anddried over MgSO4. After removal of the solvent, the residue was dissolved in methanol and asolution of NaBPh4 (1.51 g, 4.40 mmol, 1.18 equiv.) in methanol (15 mL) was added. Theforming solid was filtrated off and dried in vacuum to afford the desired product as a colorlesssolid (2.25 g, 2.69 mmol, 72 %).

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 1,3-Bis(2,6-diisopropylphenyl)imidazolium chloride, 250285-32-6

Reference£º
Article; Von Der Heiden, Daniel; Detmar, Eric; Kuchta, Robert; Breugst, Martin; Synlett; vol. 29; 10; (2018); p. 1307 – 1313;,
Chiral Catalysts
Chiral catalysts – SlideShare