Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 43142-76-3, is researched, SMILESS is O=C(C(N1)=C(C=O)C2=C1C=CC(Cl)=C2)OCC, Molecular C12H10ClNO3Journal, Organic Chemistry Frontiers called Catalytic enantioselective and regioselective substitution of 2,3-indolyldimethanols with enaminones, Author is Lu, Yi-Nan; Ma, Chun; Lan, Jin-Ping; Zhu, Caiqiang; Mao, Yu-Jia; Mei, Guang-Jian; Zhang, Shu; Shi, Feng, the main research direction is indolylmethylcyclohexenone enantioselective regioselective preparation antitumor activity; indolyl dimethanol cyclic enaminone BINOL catalyst substitution reaction.Reference of Ethyl 5-chloro-3-formyl-1H-indole-2-carboxylate.
2,3-Indolyldimethanols as a new class of indolyldimethanols were designed, and the first catalytic asym. substitution of 2,3-indolyldimethanols were established by using cyclic enaminones as nucleophiles, which afforded substitutive products in an enantioselective and regioselective mode (up to 98% ee, all >95 : 5 rr). This reaction represented the first design and application of 2,3-indolyldimethanols in catalytic asym. reactions, which greatly enriched the chem. of indolyldimethanols.
Here is a brief introduction to this compound(43142-76-3)Reference of Ethyl 5-chloro-3-formyl-1H-indole-2-carboxylate, if you want to know about other compounds related to this compound(43142-76-3), you can read my other articles.