Synthetic Route of C6H15ClN2O. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: H-Leu-NH2.HCl, is researched, Molecular C6H15ClN2O, CAS is 10466-61-2, about Enzymic synthesis of peptide in acetonitrile/supercritical carbon dioxide. Author is Noritomi, Hidetaka; Miyata, Motokazu; Kato, Satoru; Nagahama, Kunio.
The peptide synthesis from Ac-Tyr-OEt and amino acid amides was realized using α-chymotrypsin in MeCN or acetonitrile/supercritical carbon dioxide (SC-CO2) containing small amounts of water. In both solvent systems there was an optimum water content for peptide synthesis, above which peptide hydrolysis became more important. After an incubation for 5 h, the yields of the peptide was 64% in MeCN and 91% in MeCN/SC-CO2, resp.
《Enzymic synthesis of peptide in acetonitrile/supercritical carbon dioxide》 provides a strategy for the preparation of materials with excellent comprehensive properties, which is conducive to broaden the application field of this compound(H-Leu-NH2.HCl)Synthetic Route of C6H15ClN2O.