673-06-3, D-Phenylalanine is a chiral-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
673-06-3, General procedure: L-Phenylalanine (1.5 g, 9.08 mmol, 1eq.) was suspended in 30 mL of NaOH (0.39 g, 9.98 mmol, 1.1 eq.) solution and the reaction mixture was diluted with tert-butanol. To this, di-tert-butyl pyrocarbonate (2.63 mL, 10.89 mmol, 1.2 eq) was added drop-wise with constant stirring. Reaction mixture was stirred at room temperature for overnight. Next day the reaction mixture was extracted with pentane and the organic phase is extracted with saturated NaHCO3 solution (315 mL). The combined aqueous layer was acidified to pH 2 with 1N HCl solution. The acidified layer was extracted with ethyl acetate (3×25 mL) and washed with brine solution (2×15 mL). The organic layer was dried over anhydrous sodium sulphate and concentrated to give the product (2.1 g, 87.5 % yield)
The synthetic route of 673-06-3 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Kumar, Vikas; Krishna, K. Vijaya; Khanna, Shruti; Joshi, Khashti Ballabh; Tetrahedron; vol. 72; 35; (2016); p. 5369 – 5376;,
Chiral Catalysts
Chiral catalysts – SlideShare