Let’s face it, organic chemistry can seem difficult to learn. Especially from a beginner’s point of view. Like 80657-57-4, Name is (S)-Methyl 3-hydroxy-2-methylpropanoate. In a document, author is Zhu, Lixiang, introducing its new discovery. Formula: C5H10O3.
Herein, a transition-metal-free multicomponent cascade reaction of readily available alpha-halogenated ketones, ortho-aminophenols, and aldehydes using a novel dipeptide-based phosphonium salt catalyst was developed for the efficient construction of various 2H-1,4-benzoxazine derivatives with excellent functional-group tolerance. The method represents an unprecedented approach for trapping active 1,5-bifunctional intermediates with alpha-halogenated ketones to access biologically important benzoxazine scaffolds bearing two stereogenic centers with excellent asymmetric induction.
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 80657-57-4 help many people in the next few years. Formula: C5H10O3.
Reference:
Chiral Catalysts,
,Chiral catalysts – SlideShare