Chemistry, like all the natural sciences, begins with the direct observation of nature¡ª in this case, of matter.2799-17-9, Name is (S)-1-Aminopropan-2-ol, SMILES is C[C@H](O)CN, belongs to chiral-catalyst compound. In a document, author is Piekarski, Dariusz G., introduce the new discover, Safety of (S)-1-Aminopropan-2-ol.
H-bond donor catalysts able to modulate the reactivity of ionic substrates for asymmetric reactions have gained great attention in the past years, leading to the development of cooperative multidentate H-bonding supramolecular structures. However, there is still a lack of understanding of the forces driving the ion recognition and catalytic performance of these systems. Herein, insight into the cooperativity nature, anion binding strength, and folding mechanism of a model chiral triazole catalyst is presented. Our combined experimental and computational study revealed that multi-interaction catalysts exhibiting weak binding energies (approximate to 3-4 kcal mol(-1)) can effectively recognize ionic substrates and induce chirality, while strong dependencies on the temperature and solvent were quantified. These results are key for the future design of catalysts with optimal anion binding strength and catalytic activity in target reactions.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 2799-17-9 is helpful to your research. Safety of (S)-1-Aminopropan-2-ol.
Reference:
Chiral Catalysts,
,Chiral catalysts – SlideShare