The chiral-catalyst compound, name is 1,3-Bis(2,6-diisopropylphenyl)imidazolium chloride,cas is 250285-32-6, mainly used in chemical industry, its synthesis route is as follows.,250285-32-6
General procedure: A 20 mL vial was charged with the NHC¡¤HCl (300 mg, 1 equiv.) and the zinc salt (1 equiv.). Tetrahydrofuran (5 mL) was added, the vial was sealed with a screw-cap and the reaction was stirred at 60C for two hours. The mixture was allowed to reach room temperature and the solvent was removed under reduced pressure toafford the desired product. 2.2.1. Synthesis of [IPrH][ZnCl3] (4a) Colorless solid (368 mg, 93%). 1H NMR (400 MHz, CDCl3, 298 K): delta = 1.14 (d, 3JH-H = 6.9 Hz, 12H, CH-CH3), 1.31 (d, 3JH-H = 6.9 Hz, 12H, CH-CH3), 2.53 (sept, 3JH-H = 6.9 Hz, 4H, CH-CH3), 7.32 (d, 3JH-H = 7.7 Hz, 4H, CH phenyl), 7.55 (t, 3JH-H = 7.8 Hz, 2H, CH phenyl), 8.00 (s, 1H, H2), 8.46 (s, 2H, H4 and H5). 13C-{1H} NMR (75 MHz, CDCl3, 298 K): delta = 24.0 (s, CH-CH3), 25.0 (s, CH-CH3), 29.0 (s, CH-CH3), 124.8 (s, CH Ar), 128.6 (s, CH Ar), 129.9 (s, CIV), 132.2 (s, CIV), 134.3 (s, C2), 145.6 (s, C4 and C5). Anal. Calcd for C27H37Cl3N2Zn: C, 57.77; H, 6.64; N, 4.99. Found: C, 57.84; H, 6.61; N, 5.05.
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Reference£º
Article; Santoro, Orlando; Nahra, Fady; Cordes, David B.; Slawin, Alexandra M.Z.; Nolan, Steven P.; Cazin, Catherine S.J.; Journal of Molecular Catalysis A: Chemical; vol. 423; (2016); p. 85 – 91;,
Chiral Catalysts
Chiral catalysts – SlideShare