Electric Literature of 21436-03-3. Let’s face it, organic chemistry can seem difficult to learn. Especially from a beginner’s point of view. Like 21436-03-3, Name is (1S,2S)-Cyclohexane-1,2-diamine. In a document type is Article, introducing its new discovery.
The development of methods for the selective and atom-economic oxidation/oxygenation of organic substrates belongs to the most challenging fields of contemporary chemical research, both in the academic and the industrial environment (1). Whereas breath-taking turnover numbers and selectivities have been achieved for numerous reductive processes (such as catalytic asymmetric hydrogenation) (2), oxidative transformations such as the epoxidation of olefins still lag behind. Biomimetic oxidation catalysis aims at achieving the efficiencies and selectivities of enzymes, such as monooxygenases or peroxidases, with low-molecular weight compounds (3). The design of biomimetic oxidation catalysts is based on the active-site structure and function of oxidative enzymes. For the sake of atom-economy and sustainability, terminal oxidants such as molecular oxygen or dihydrogen peroxide are employed preferentially (3). It is an intrinsic feature of biomimetic oxidation catalysts that they aim at imitating soluble enzymes, which means that they are generally homogeneous in nature. In some cases, immobilized variants have been prepared and will be discussed as well. On the other hand, purely heterogeneous (and non-biomimetic) oxidation catalysts such as transition metal mixed oxides or silicalites are not covered by this chapter. The majority of the homogeneous and biomimetic oxidation catalysts being investigated to date fall into two classes: (i) Metal-ligand (peptidic or non-peptidic) combinations, (ii) metal-free organocatalysts. Typical reactions effected by the former are electrophilic oxygen transfer to e.g., C{double bond, long}C double bonds or other nucleophilic substrates (such as thioethers), whereas the latter have been used both for this purpose and to effect the addition of nucleophilic oxidants to acceptors such as enones.
If you are interested in 21436-03-3, you can contact me at any time and look forward to more communication.Electric Literature of 21436-03-3