Chemistry, like all the natural sciences, Safety of (R)-3-(2-Amino-2-oxoethyl)-5-methylhexanoic acid, begins with the direct observation of nature¡ª in this case, of matter.181289-33-8, Name is (R)-3-(2-Amino-2-oxoethyl)-5-methylhexanoic acid, SMILES is CC(C)C[C@H](CC(N)=O)CC(O)=O, belongs to chiral-catalyst compound. In a document, author is Iwan, Dominika, introduce the new discover.
In a search for new, selective antitumor agents, we prepared a series of sulfonamides built on bicyclic scaffolds of 2-azabicyclo(2.2.1)heptane and 2-azabicyclo(3.2.1)octane. To this end, aza-Diels-Alder cycloadducts were converted into amines bearing 2-azanorbornane or a bridged azepane skeleton; their treatment with sulfonyl chlorides containing biaryl moieties led to the title compounds. The study of antiproliferative activity of the new agents showed that some of them inhibited the growth of chosen cell lines with the IC50 values comparable with cisplatin, and some derivatives were found considerably less toxic for nonmalignant cells.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 181289-33-8. Safety of (R)-3-(2-Amino-2-oxoethyl)-5-methylhexanoic acid.
Reference:
Chiral Catalysts,
,Chiral catalysts – SlideShare