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Highly N2-selective coupling of 1,2,3-triazoles with indole and pyrrole
Hydrogen-bond mediated coupling of 1,2,3-triazoles to indoles and pyrroles results in N2 selective functionalization of the triazole moiety in moderate to excellent yields. The reaction was tolerant of un-, mono- and disubstituted triazoles and was applied to synthesize tryptophan derived fluorescent amino acids. Copyright
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Reference£º
Chiral Catalysts,
Chiral catalysts – SlideShare