A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 4254-14-2, Name is (R)-Propane-1,2-diol, molecular formula is C3H8O2. In an article, author is Lima, Yanka R.,once mentioned of 4254-14-2, HPLC of Formula: C3H8O2.
Herein, we described a simple and efficient protocol for the synthesis of alpha-hydroxyphosphonates containing 1,2,3-triazole moiety in their structures under mild conditions. This approach was performed by Abramov reaction in a solvent-free system, using Na2CO3 as catalyst at 70 degrees C, which provided the desired products from moderate to excellent yields. The substrate scope was effective for different organic functions, such as ester, ketone, and amide. The synthetic route is modulated by the presence of a bulky group at the hydrophosphoryl reagent, avoiding steric hindrance, since the Abramov reaction can be approached before the Click-Chemistry protocol. The synthesis can also be carried out in a one-pot method, minimizing costs, and without side reactions. Additionally, the chiral discrimination of the synthesized products was easily accessed by H-1 and P-31 nuclear magnetic resonance experiments, using a chiral solvating agent.
Interested yet? Keep reading other articles of 4254-14-2, you can contact me at any time and look forward to more communication. HPLC of Formula: C3H8O2.
Reference:
Chiral Catalysts,
,Chiral catalysts – SlideShare