One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, such as the rate of change in the concentration of reactants or products with time. 80657-57-4, Name is (S)-Methyl 3-hydroxy-2-methylpropanoate, formurla is C5H10O3. In a document, author is Lai, Yu-Ting, introducing its new discovery. Computed Properties of C5H10O3.
An organocatalytic enantioselective synthesis of delta-lactone-fused 4-chromanones was demonstrated using 1-(2-hydroxyaryl)-1,3-butanedione and alpha,beta-unsaturated aldehydes in the presence of the Jorgensen-Hayashi catalyst. The reaction proceeded through a Michael addition/cycloketalization/hemiacetalization sequence, and the resulting hemiacetals were oxidized into the corresponding lactone derivatives in a one-pot manner. The desired fusedO,O-ketal tricyclic lactone motifs containing three contiguous chiral centers were obtained in excellent chemical yields (up to 97%) and with high stereoselectivities (up to >20:1 dr and up to 95% ee).
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Reference:
Chiral Catalysts,
,Chiral catalysts – SlideShare