2133-34-8, (S)-Azetidine-2-carboxylic acid is a chiral-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Synthesis of Azethidine-2-carboxylic Acid N-carboxyamino Acid Anhydride At room temperature, (S)-azethidine-2-carboxylic acid (1.0 g, 99.9% ee or higher) was suspended in 25 ml of tetrahydrofuran. Then tri-phosgene (1.0 g) was added thereto. The suspension was heated to 50 C. and stirred for 4 hours. After allowing to cool, the solvent was distilled off under reduced pressure to give a pale yellow oil (1.5 g). 1H-NMR(CDC13) delta 4.52 (dd, 1H), 3.76-3.62 (m, 2H), 2.44-2.36 (m, 1H), 2.23-2.14 (m, 1H), 13C-NMR (CDC13) delta 169.10, 152.27, 55.44, 40.37, 34.22.
2133-34-8 (S)-Azetidine-2-carboxylic acid 16486, achiral-catalyst compound, is more and more widely used in various.
Reference£º
Patent; Matsuo, Kazuhiko; Tsukuya, Kentaro; US2002/151721; (2002); A1;,
Chiral Catalysts
Chiral catalysts – SlideShare