In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called α,α-Disubstituted butanolides. Preparation of 2-bromo-2-methylbutanolide. New synthesis for 2-hydroxy-2-methylbutanolide, published in 1973, which mentions a compound: 542-58-5, mainly applied to butanolide bromo hydroxy; malonate chloroethanol cyclization, Reference of 2-Chloroethyl acetate.
Butanolides I (R = CO2Et, H) were obtained by cyclizing NaCMe(CO2Et)2 with ClCH2CH2OH or ClCH2CH2OAc. I (R = CO2Et) was decarboxylated in boiling 3N HCl. I (R = H) was brominated with PBr3 and the I (R = Br) hydrolyzed to I (R = OH).
Compounds in my other articles are similar to this one(2-Chloroethyl acetate)Reference of 2-Chloroethyl acetate, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.