Brief introduction of 63126-47-6

63126-47-6 (S)-2-(Methoxymethyl)pyrrolidine 671217, achiral-catalyst compound, is more and more widely used in various.

63126-47-6, (S)-2-(Methoxymethyl)pyrrolidine is a chiral-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,63126-47-6

Method B Methyl bromoacetate (199 pI, 2.10 mmol) was added to a mixture of (S)-2- methoxymethyl pyrrolidine (268 pI, 2.17 mmol), potassium carbonate (319 mg, 2.31 mmol) and sodium iodide (315 mg, 2.10 mmol) in acetonitrile (3 ml). The mixture was subjected to microwave irradiation for 5 min at 160¡ãC, then partitioned between dichloromethane and water. The aqueous layer was extracted with dichloromethane and the combined organic layers were washed with brine, dried over sodium sulfate and concentrated in vacuo. Purification by flash column chromatography eluting with 0-10percent (v/v) methanol in dichloromethane afforded (S)- (2-methoxymethyl-pyrrolidin-1- yl) acetic acid methyl ester (133 mg, 0.71 mmol).

63126-47-6 (S)-2-(Methoxymethyl)pyrrolidine 671217, achiral-catalyst compound, is more and more widely used in various.

Reference£º
Patent; AKZO NOBEL N.V.; WO2005/89754; (2005); A1;,
Chiral Catalysts
Chiral catalysts – SlideShare