Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, Quality Control of (2R,3R)-2,3-Dihydroxysuccinic acid, 87-69-4, Name is (2R,3R)-2,3-Dihydroxysuccinic acid, SMILES is O=C(O)[C@H](O)[C@@H](O)C(O)=O, belongs to chiral-catalyst compound. In a document, author is Zhu, Lixiang, introduce the new discover.
Herein, a transition-metal-free multicomponent cascade reaction of readily available alpha-halogenated ketones, ortho-aminophenols, and aldehydes using a novel dipeptide-based phosphonium salt catalyst was developed for the efficient construction of various 2H-1,4-benzoxazine derivatives with excellent functional-group tolerance. The method represents an unprecedented approach for trapping active 1,5-bifunctional intermediates with alpha-halogenated ketones to access biologically important benzoxazine scaffolds bearing two stereogenic centers with excellent asymmetric induction.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 87-69-4. Quality Control of (2R,3R)-2,3-Dihydroxysuccinic acid.
Reference:
Chiral Catalysts,
,Chiral catalysts – SlideShare