Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 4254-14-2, Name is (R)-Propane-1,2-diol, molecular formula is C3H8O2, belongs to chiral-catalyst compound. In a document, author is Lou, Shao-Jie, introduce the new discover, Quality Control of (R)-Propane-1,2-diol.
The enantioselective C-H alkenylation of ferrocenes with alkynes is, in principle, a straightforward and atom-efficient route for the construction of planar-chiral ferrocene scaffolds bearing alkene functionality but has remained scarcely explored to date. Here we report for the first time the highly enantioselective C-H alkenylation of quinoline- and pyridine-substituted ferrocenes with alkynes by a half-sandwich scandium catalyst. This protocol features broad substrate scope, high enantioselectivity, and 100% atom efficiency, selectively affording a new family of planar-chiral ferrocenes bearing N/alkene functionalities. The mechanistic details have been clarified by DFT analyses. The use of a quinoline/alkene-functionalized ferrocene product as a chiral ligand for asymmetric catalysis is also demonstrated.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 4254-14-2. Quality Control of (R)-Propane-1,2-diol.
Reference:
Chiral Catalysts,
,Chiral catalysts – SlideShare