Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, the author is Chen, Zhengwang and a compound is mentioned, 1806-29-7, 2,2-Biphenol, introducing its new discovery. 1806-29-7
Formal Direct Cross-Coupling of Phenols with Amines
The transition-metal-catalyzed amination of aryl halides has been the most powerful method for the formation of aryl amines over the past decades. Phenols are regarded as ideal alternatives to aryl halides as coupling partners in cross-couplings. An efficient palladium-catalyzed formal cross-coupling of phenols with various amines and anilines has now been developed. A variety of substituted phenols were compatible with the standard reaction conditions. Secondary and tertiary aryl amines could thus be synthesized in moderate to excellent yields.
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Reference£º
Chiral Catalysts,
Chiral catalysts – SlideShare