6381-59-5, Name is Potassium sodium tartrate tetrahydrate, molecular formula is C4H12KNaO10, COA of Formula: C4H12KNaO10, belongs to chiral-catalyst compound, is a common compound. In a patnet, author is Jiang, Sheng-Peng, once mentioned the new application about 6381-59-5.
A copper-catalyzed enantioconvergent Suzuki-Miyaura C(sp(3))-C(sp(2)) cross-coupling of various racemic alkyl halides with organoboronate esters has been established in high enantioselectivity. Critical to the success is the use of a chiral cinchona alkaloid-derived N,N,P-ligand for not only enhancing the reducing capability of copper catalyst to favor a stereoablative radical pathway over a stereospecific S(N)2-type process but also providing an ideal chiral environment to achieve the challenging enantiocontrol over the highly reactive radical species. The reaction has a broad scope with respect to both coupling partners, covering aryl- and heteroarylboronate esters, as well as benzyl-, heterobenzyl-, and propargyl bromides and chlorides with good functional group compatibility. Thus, it provides expedient access toward a range of useful enantioenriched skeletons featuring chiral tertiary benzylic stereocenters.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 6381-59-5. The above is the message from the blog manager. COA of Formula: C4H12KNaO10.
Reference:
Chiral Catalysts,
,Chiral catalysts – SlideShare