Category: 141556-45-8

1,3-Dimesityl-1H-imidazol-3-ium chloride, cas is 141556-45-8, it is a common heterocyclic compound, the chiral-catalyst compound, its synthesis route is as follows.,141556-45-8

In analogy to S. P. Nolan, Organometallics 1999, 18, 5416-5419, a suspension of 1.55 g (4.33 mmol) of 1,3-bis(2,4,6-trimethylphenyl)-imidazolium chloride (commercially available from Strem Chemicals Inc., D-77672 Kehl) and 2.70 ml (4.59 mmol) of potassium tert.-pentylate (1.7 M in toluene) was suspended in 20 ml hexane and heated at 50 C. for 10 min. 2.00 g (2.17 mmol) of [RuCl2(Pcy3)2(3-phenyl-indenylidene)] was added and the resulting red suspension stirred at 50 C. for 15 h. The reaction mixture was allowed to cool to r.t., the formed brown crystals were filtered off and washed with 40 ml pentane. The crystals were dissolved in 30 ml dichloromethane. 30 ml water was added and the organic layer was separated and dried over Na2SO4. The orange solution was evaporated to dryness and the isolated red crystals washed with 30 ml pentane and dried under vacuum to yield 2.05 g (81% yield) of the title compound. MS: 946.3 (M+). 31P-NMR (121 MHz, C6D6): 27.4 ppm. 1H-NMR (300 MHz, C6D6): 1.00-1.40 (m, 18H); 1.47-1.68 (m, 6H); 1.70-1.84 (m, 3H); 1.80 (s, 3H); 1.85-1.95 (m, 3H); 2.04 (s, 3H); 2.20 (s, 3H); 2.24 (s, 3H); 2.45-2.60 (m, 3H); 2.65 (s, 3H); 2.67 (s, 3H); 6.03 (s, 1H); 6.16 (s, 2H); 6.47 (s, 1H); 6.95 (s, 2H); 7.10-7.37 (m, 6H); 7.85 (s, 1H); 7.87-7.93 (m, 2H); 9.12 (d, 1H, J=6.8 Hz). Anal. calcd. for C54H67N2Cl2PRu: C, 68.48; H, 7.13; N, 2.96; Cl, 7.49. Found: C, 68.71; H, 7.11; N, 3.77; Cl, 7.37.

With the synthetic route has been constantly updated, we look forward to future research findings about 1,3-Dimesityl-1H-imidazol-3-ium chloride,belong chiral-catalyst compound

Reference£º
Patent; Puentener, Kurt; Scalone, Michelangelo; US2006/241156; (2006); A1;,
Chiral Catalysts
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1,3-Dimesityl-1H-imidazol-3-ium chloride, cas is 141556-45-8, it is a common heterocyclic compound, the chiral-catalyst compound, its synthesis route is as follows.,141556-45-8

General procedure: Under a N2 atmosphere, a mixture of imidazolium salts 1(0.225 mmol), PdCl2 (0.15 mmol), K2CO3 (0.45 mmol) and picolinicacid 2 (0.15 mmol) was stirred in anhydrous THF (2.0 mL) underreux for 12 h. Then the solvent was removed under reducedpressure, and the residue was puried by ash column chroma-tography (SiO2) to give complexes 3 as yellow solids.

With the rapid development of chemical substances, we look forward to future research findings about 1,3-Dimesityl-1H-imidazol-3-ium chloride

Reference£º
Article; Zhang, Zhi-Mao; Gao, Yu-Jue; Lu, Jian-Mei; Tetrahedron; vol. 73; 52; (2017); p. 7308 – 7314;,
Chiral Catalysts
Chiral catalysts – SlideShare

As a common heterocyclic compound, it belongs to quinuclidine compound,Quinuclidine-4-carboxylic acid hydrochloride,40117-63-3,Molecular formula: C8H14ClNO418,mainly used in chemical industry, its synthesis route is as follows.,141556-45-8

General procedure: To a solution of the dimeric Ni(II)-complex in THF (20 mL) wasadded the respective imidazolium chloride (2 equiv.) and KOtBu(2.3 equiv.) or NaHMDS (2.3 equiv.). The reaction mixture washeated to 60 C for 2 h and then left at room temperature overnight.The solvent was removed under reduced pressure and the residuewas extracted into CH2Cl2. This CH2Cl2 solutionwas passed througha short column of alumina. The eluting orange-brown solution wassubsequently evaporated to dryness. Diffusion of cyclohexane intoa THF solution afforded orange-brown crystals after several days.Samples for elemental analysis were further recrystallised fromMeOH.

With the synthetic route has been constantly updated, we look forward to future research findings about 1,3-Dimesityl-1H-imidazol-3-ium chloride,belong chiral-catalyst compound

Reference£º
Article; Clauberg, Maximilian H.; Schmidt, Darya; Rust, Joerg; Lehmann, Christian W.; Arefyeva, Natalia; Wickleder, Mathias; Mohr, Fabian; Journal of Organometallic Chemistry; vol. 881; (2019); p. 45 – 50;,
Chiral Catalysts
Chiral catalysts – SlideShare

141556-45-8, 1,3-Dimesityl-1H-imidazol-3-ium chloride is a chiral-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

IMesHCl (0.503 g, 1.47 mmol) was loaded into an oven-dried 100 mL Schlenk flask and placed under a nitrogen atmosphere. Dry degassed THF (50mL) was added to the flask via cannula and a white slurry formed. The slurry was chilled to -78C in a dry ice/acetone bath and 1.OOmL of 1.6M nBuLi in hexane (1.6mmol) was added drop-wise. This reaction mixture was stirred for 30 minutes in the cold bath followed by 2 hours out of the bath to generate free carbene. The flask was then cooled a second time to -78C followed by addition of freshly distilled TMEDA (0.97 mL; 6.47 mmol) and 1.00 mL of 1.6 M nBuLi. The reaction mixture was stirred for 2 hours at -78C followed by addition of Mes2BF (0.473 g, 1.76 mmol). The reaction mixture was stirred for 3 hours while at -78C before warming to room temperature and stirring overnight. The resulting mixture was quenched with water and extracted with diethyl ether. An organic extract was dried over MgS04 followed by removal of volatiles in vaccuo. A resulting solid was dissolved in a minimum of diethyl ether and was precipitated by addition of hexane. The solid was collected by vacuum filtration and 0.723 g (89%) of the chelate product SMI was collected. X-ray quality crystals were grown using a saturated solution of THF layered with hexanes. 1H NMR (C6D6): delta = 1.67 (s, 3H, ArCH3), 1.68 (s, 3H, ArCH3), 1.85 (s, 3Eta, ArCH3), 2.04 (s, 3Eta, ArCH3), 2.07 (s, 3Eta, ArCH3), 2.08 (s, 3Eta, ArCH , 2.08 (s, 3Eta, ArCH3), 2.13 (s, 3Eta, ArCH3), 2.17 (s, 3Eta, ArCH3), 2.46 (s, 3Eta, ArCH3), 2.84 (d, 1Eta, 3JHH = 12.0 Hz, B-CH2), 2.88 (s, 3Eta, ArCH3), 3.06 (d, 1Eta, 3JHH = 12.0 Hz, B-CH2), 5.78 (d, 1H, 3JHH = 4.0 Hz, Imidazole-CH), 5.97 (s, 1H, ArH), 6.18 (s, 1Eta, ArH), 6.48 (s, 1Eta, ArH), 6.52 (s, 1Eta, ArH), 6.52 (s, 1Eta, ArH), 6.62 (d, 1 Eta, 3JHH = 4.0 Hz, Imidazole-CH), 6.72 (s, 1Eta, ArH), 6.73 (s, 1Eta, ArH), 6.73 (s, 1Eta, ArH). nB NMR (C6D6): delta = -1 1.2. 13C {} NMR (C6D6): delta = 19.1 (ArCH3), 19.1 (ArCH3), 20.0 (Ar H3), 20.8 (Ar H3), 20.8 (Ar H3), 21.0 (ArCH3), 21.0 (ArCH3), 24.0 (ArCH3), 24.9 (ArCH3), 27.7 (ArCH3), 27.9 (Ar H3), 33.5 (located by HSQC, B- H2), 120.0 (Imidazole-CH), 121.3 (Imidazole-CH), 125.3 (ArQ, 125.7 (ArQ, 6 ArCH located under the solvent signal via HSQC , 129.0 (ArCH), 130.3 (ArQ, 130.8 (ArCH), 131.5 (ArQ, 131.9 (ArQ, 133.0 (ArQ, 133.1 (ArQ, 134.4 (ArQ, 135.9 (ArQ, 137.0 (ArQ, 138.3 (ArQ, 138.7 (ArQ, 141.3 (ArQ, 141.9 (ArQ, 143.1 (ArQ, 145.4 (ArQ, 207.4 (N-C-N). Anal. Calcd. for C39H45N2B: C, 84.77; H, 8.21 ; N, 5.07., 141556-45-8

The synthetic route of 141556-45-8 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; LU, Jiasheng; WANG, Suning; KO, Soo-Bying; MCDONALD, Sean, Michael; YANG, Dengtao; WO2014/153648; (2014); A1;,
Chiral Catalysts
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Name is 1,3-Dimesityl-1H-imidazol-3-ium chloride, as a common heterocyclic compound, it belongs to chiral-catalyst compound, and cas is 141556-45-8, its synthesis route is as follows.,141556-45-8

Under the protection of nitrogen, to the reaction tube is sequentially added imidazole salt IMes¡¤HCl (1.1mmol), palladium chloride (1.0mmol), potassium carbonate (2.2mmol), tetrahydrofuran (5.0 ml) and isoquinoline (2.0mmol). The mixture is placed in the oil bath heated reaction (80 C) 12 hours. Stopping the reaction, cooling to room temperature, pressure reducing turns on lathe does solvent, rapid column chromatography separation to obtain a yellow solid product 0.0927g, yield 76%.

With the complex challenges of chemical substances, we look forward to future research findings about 1,3-Dimesityl-1H-imidazol-3-ium chloride

Reference£º
Patent; Wenzhou University; Shao Lixiong; Lu Jianmei; Liu Feng; (23 pag.)CN106892945; (2017); A;,
Chiral Catalysts
Chiral catalysts – SlideShare

1,3-Dimesityl-1H-imidazol-3-ium chloride, cas is 141556-45-8, it is a common heterocyclic compound, the chiral-catalyst compound, its synthesis route is as follows.,141556-45-8

Synthesis of [(IMes)CuCl]. This synthesis is as reported in the literature; see S. Okamoto et al., J. Organomet. Chem. 2005, 690, 6001-6007. Tetrahydrofuran (7 mL) was added to a mixture of 1,3-bis(2,4,6-trimethylphenyl)imidazolium chloride (IMes-HCl, 1 mmol), CuCl (0.9 mmol), and sodium tert-butoxide (1 mmol). The suspension was stirred for 6 hours at room temperature, and then filtered through a pad of Celite. The filtrate was dried under vacuum. 1H NMR (500 MHz, CDCl3) delta=7.06 (s, 2H), 7.00 (s, 4H), 2.34 (s, 6H), 2.30 (d, 12H); 13C NMR (125 MHz, CDCl3) delta=178.7, 139.2, 134.9, 134.4, 129.3, 122.2, 21.1, 17.6; IR (KBr) 2914, 1485, 1400, 1234, 1076, 932, 862, 702 cm-1; Elemental analysis calcd for C21H24CuClN2: C, 62.52; H, 6.00; N, 6.94. Found: C, 62.33; H, 6.16; N, 6.86%.

141556-45-8 is used more and more widely, we look forward to future research findings about 1,3-Dimesityl-1H-imidazol-3-ium chloride

Reference£º
Patent; Institut Catala d’Investigacio Quimica; Institucio Catalana de Recerca i Estudis Avancats; US2009/69569; (2009); A1;,
Chiral Catalysts
Chiral catalysts – SlideShare

1,3-Dimesityl-1H-imidazol-3-ium chloride, cas is 141556-45-8, it is a common heterocyclic compound, the chiral-catalyst compound, its synthesis route is as follows.,141556-45-8

General procedure: A mixture of pyrazine ligand 1 or 2 (1mmol), Li2PdCl4 (1mmol) and NaOAc (1mmol) in 20mL of dry methanol was stirred for 24hat rt. The yellow solids (yield: 92%) were collected by filtration and washed several times with methanol, which can be assigned to be palladacyclic dimers. Then, a Schlenk tube was charged with the above chloride-bridged palladacyclic dimers (0.5mmol), the corresponding imidazolium salt (1.25mmol) and tBuOK (2.5mmol) under nitrogen. Dry THF was added by a cannula and stirred at room temperature for 3h. The product was separated by passing through a short silica gel column with CH2Cl2 as eluent, the third band was collected and afforded the corresponding carbene adducts 3-10 as yellow solids. The characterization data for 3: Yield: 78%.

As the rapid development of chemical substances, we look forward to future research findings about 141556-45-8

Reference£º
Article; Xu, Chen; Wang, Zhi-Qiang; Fu, Wei-Jun; Ji, Bao-Ming; Yuan, Xiao-Er; Han, Xin; Xiao, Zhi-Qiang; Hao, Xin-Qi; Song, Mao-Ping; Journal of Organometallic Chemistry; vol. 777; (2015); p. 1 – 5;,
Chiral Catalysts
Chiral catalysts – SlideShare

141556-45-8, 1,3-Dimesityl-1H-imidazol-3-ium chloride is a chiral-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Under the protection of nitrogen, to the reaction tube is sequentially added imidazole salt IMes¡¤HCl (1.1mmol), palladium chloride (1.0mmol), potassium carbonate (2.2mmol), tetrahydrofuran (5.0 ml) and isoquinoline (2.0mmol). The mixture is placed in the oil bath heated reaction (80 C) 12 hours. Stopping the reaction, cooling to room temperature, pressure reducing turns on lathe does solvent, rapid column chromatography separation to obtain a yellow solid product 0.0927g, yield 76%.

141556-45-8, As the paragraph descriping shows that 141556-45-8 is playing an increasingly important role.

Reference£º
Patent; Wenzhou University; Shao Lixiong; Lu Jianmei; Liu Feng; (23 pag.)CN106892945; (2017); A;,
Chiral Catalysts
Chiral catalysts – SlideShare

As a common heterocyclic compound, it belongs to chiral-catalyst compound, name is 1,3-Dimesityl-1H-imidazol-3-ium chloride, and cas is 141556-45-8, its synthesis route is as follows.

A butterfly for the keto-carbonyl of bridge [2Fe2Se] kind of iron-iron hydrogenase models object 5 preparation method, the chemical formula of the model [( mu-SeCH 2 (CO) CH 2 Se-mu)] Fe 2 (CO) 5 (IMes) (IMes=1,3-b (2, 4, 6-trimethyl phenyl) imidazole-2-carbene), shown in the preparing process is as follows. Specific preparation steps are as follows: 1) in high purity under the protection of nitrogen, with stirring to the drying of the magneton 100 ml reaction flask by adding 455 mg (1.336mmol) 1,3-bis (2, 4, 6-trimethyl phenyl) imidazole hydrochloride and 20 ml tetrahydrofuran, shall be mixed solution; 2) in the above-mentioned mixed solution is added with 1.6Mn-BuLi solution 1 ml, stirring the mixture at room temperature for 20 min, the reaction liquid obtained, the above-mentioned reaction solution is then filtered, and the filtrate by adding in 165 mg (0.334mmol) 1 further reaction to obtain a reaction mixture; 3) the above-mentioned reaction mixture, the solvent is pumped under reduced pressure, the residue is extracted with methylene chloride, the volume ratio of 1:1 mixture of dichloromethane-petroleum ether as a developing agent thin layer chromatographic separation, collection red the main ribbon, obtain a red solid 159 mg, the chemical formula is [( mu-SeCH 2 (CO) CH 2 Se-mu)] Fe 2 (CO) 5 (IMes) (5), the yield is 62%.

141556-45-8, In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles.,141556-45-8 ,1,3-Dimesityl-1H-imidazol-3-ium chloride, other downstream synthetic routes, hurry up and to see

Reference£º
Patent; Nankai University; Song, Licheng; Han, Xiaofeng; Song, Fengtao; (7 pag.)CN105294777; (2016); A;,
Chiral Catalysts
Chiral catalysts – SlideShare

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.141556-45-8,1,3-Dimesityl-1H-imidazol-3-ium chloride,as a common compound, the synthetic route is as follows.

General procedure: Under an N2 atmosphere, the mixture of imidazolium salts 1 (1.1 mmol), benzoxazole or benzothiazole (2.0 mmol), PdCl2 (1.0 mmol) and K2CO3 (1.1 mmol) was stirred in anhydrous THF (10 mL) under reflux for 16 h. After cooling, filtration and evaporation,the residue was purified by preparative TLC on silica gelplates eluting with CH2Cl2 to afford the corresponding N-heterocyclic carbene-palladium(II) complexes 3a-d., 141556-45-8

141556-45-8 1,3-Dimesityl-1H-imidazol-3-ium chloride 2734211, achiral-catalyst compound, is more and more widely used in various fields.

Reference£º
Article; Wang, Tao; Xie, Huanping; Liu, Lantao; Zhao, Wen-Xian; Journal of Organometallic Chemistry; vol. 804; (2016); p. 73 – 79;,
Chiral Catalysts
Chiral catalysts – SlideShare