Category: 141556-45-8

141556-45-8, 1,3-Dimesityl-1H-imidazol-3-ium chloride is a chiral-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

V-heterocyclic carbenes were synthesized from their corresponding imidazolium or imidazolinium salts (see Table 1 ). About 0.8 eq. of potassium tert- butoxide (8.9 mg) and 1 eq. of a 1 , 3-disubstituted imidazolium salt (Table 1 , entries 1 – 5) or 1 , 3-disubstituted imidazolinium salt (Table 1 , entry 7) was dissolved in 2 ml_ of tetrahydrofuran (THF). The reaction was stirred for 1 h under argon protection at ambient temperature. The solvent was then removed in vacuo. The resulting carbene was used without further purification and was characterized by 1H NMR and mass spectrometry., 141556-45-8

The synthetic route of 141556-45-8 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; SOUTHERN ILLINOIS UNIVERSITY CARBONDALE; WO2008/70756; (2008); A2;,
Chiral Catalysts
Chiral catalysts – SlideShare

A common heterocyclic compound, the chiral-catalyst compound, name is 1,3-Dimesityl-1H-imidazol-3-ium chloride,cas is 141556-45-8, mainly used in chemical industry, its synthesis route is as follows.,141556-45-8

Prepared according a procedure of Mohr et al.21 To a soln of1,3-bis(2,4,6-trimethylphenyl)imidazolium chloride (175 mg,0.513 mmol) in CH2Cl2 (10 mL) was added HgO (108 mg,0.514 mmol) and Me4NCl (56.4 mg, 0.51 mmol). After stirring at r.t. for 15 h, the soln was passed through Celite, the solvent was removed in vacuo, and the residue was washed with H2O (2 ¡Á 10 mL) and Et2O (2 ¡Á 10 mL) to give 14 as a colorless solid; yield: 240 mg (82%); mp 270 C (dec); Rf = 0.09 (CH2Cl2-MeOH, 10:1).

As the rapid development of chemical substances, we look forward to future research findings about 141556-45-8

Reference£º
Article; Emsermann, Jens; Arduengo, Anthonyj.; Opatz, Till; Synthesis; vol. 45; 16; (2013); p. 2251 – 2264;,
Chiral Catalysts
Chiral catalysts – SlideShare

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.141556-45-8,1,3-Dimesityl-1H-imidazol-3-ium chloride,as a common compound, the synthetic route is as follows.

General procedure: A mixture of pyrazine ligand 1 or 2 (1mmol), Li2PdCl4 (1mmol) and NaOAc (1mmol) in 20mL of dry methanol was stirred for 24hat rt. The yellow solids (yield: 92%) were collected by filtration and washed several times with methanol, which can be assigned to be palladacyclic dimers. Then, a Schlenk tube was charged with the above chloride-bridged palladacyclic dimers (0.5mmol), the corresponding imidazolium salt (1.25mmol) and tBuOK (2.5mmol) under nitrogen. Dry THF was added by a cannula and stirred at room temperature for 3h. The product was separated by passing through a short silica gel column with CH2Cl2 as eluent, the third band was collected and afforded the corresponding carbene adducts 3-10 as yellow solids. The characterization data for 3: Yield: 78%., 141556-45-8

As the paragraph descriping shows that 141556-45-8 is playing an increasingly important role.

Reference£º
Article; Xu, Chen; Wang, Zhi-Qiang; Fu, Wei-Jun; Ji, Bao-Ming; Yuan, Xiao-Er; Han, Xin; Xiao, Zhi-Qiang; Hao, Xin-Qi; Song, Mao-Ping; Journal of Organometallic Chemistry; vol. 777; (2015); p. 1 – 5;,
Chiral Catalysts
Chiral catalysts – SlideShare

The chiral-catalyst compound, name is 1,3-Dimesityl-1H-imidazol-3-ium chloride,cas is 141556-45-8, mainly used in chemical industry, its synthesis route is as follows.,141556-45-8

Finely powdered PdCl2 (177 mg, 1.00 mmol) was suspended in CH3CN (5 mL) and N-benzyldimethylamine (160 muL, 143 mg, 1.05 mmol) were added. The solution was heated to 8O0C with stirring until a clear, orange solution was formed (approx. 20 min). Finely powdered K2CO3 (691 mg, 5.00 mmol) was added and the stirring was continued until palladacycle formation was complete, as indicated by the formation of a canary yellow solution (5-10 min). IMesetaCl (375 mg, 1.10 mmol) was added and the mixture was stirred at 8O0C over 18h. The reaction mixture was filtered and evaporated. The resulting product was purified by column chromatography. Upon application of the product to a pad of silica gel (2.5 x 8 cm) pre-equilibrated with CH2CI2, CH2CI2 (100 mL) was used to elute impurities. The pure NHC-palladacycles were eluted with CH2Cl2-ethylacetate (3:1, vol/vol, 150 mL), and the solvent was evaporated. The products were triturated with hexanes (25 mL). After drying in high vacuum, IMes-Pd(dmba)Cl (555 mg, 96%) was obtained as beige solid. 1H NMR (CDCl3, 400 MHz) delta: 7.10 (s, 2H), 6.99 (s, 2H), 6.83-6.76 (m, 4H), 6.70 (td, J= 7.6, 1.2 Hz, IH), 6.58 (d, J= 7.2, 1.2 Hz, IH), 3.53 (s, 2H), 2.45 (s, 6H), 2.44 (s, 6H), 2.29 (s, 6H), 2.23 (s, 6H). 13C NMR (CDCl3, 100 MHz) delta: 175.6, 149.3, 147.6, 138.3, 138.3, 137.4, 136.2, 133.9, 129.4, 128.7, 123.9, 123.2, 123.0, 121.2, 72.2, 50.0, 21.1, 20.2, 19.8. Anal, calcd for C30H37ClN3Pd (581.51): C, 61.96; H, 6.41; N, 7.23. Found: C, 62.02; H, 6.37; N, 7.40.

As the rapid development of chemical substances, we look forward to future research findings about 141556-45-8

Reference£º
Patent; AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH; WO2008/156451; (2008); A1;,
Chiral Catalysts
Chiral catalysts – SlideShare

The chiral-catalyst compound, name is 1,3-Dimesityl-1H-imidazol-3-ium chloride,cas is 141556-45-8, mainly used in chemical industry, its synthesis route is as follows.,141556-45-8

General procedure: [HIPr]2[PdCl4]: 0.45 g (1.0 mmol) of [HIPr]Cl was added to thesolution of 0.14 g (0.48 mmol) PdCl2(cod) in hot CH3CN (5 mL). Themixture was heated for 15 min, until the yellow solution becamered. The solution was cooled to room temperature and solventwas removed under reduced pressure. The product was precip-itated by addition of diethyl ether (2-3 mL). Product yield: 85%;elemental analysis calcd. (%) for PdCl4C54H78N4: C 62.88, H 7.62,N 5.46; found: C 62.37, H 7.46, N 5.40.1H NMR(500 MHz, CD3CN,25C, TMS): = 8.49 (s, 2H, N CH N); 7.57 (t, J(H,H) = 7.8 Hz, 4H,Ar); 7.42 (d, J(H,H) = 7.8 Hz, 8H, Ar); 4.48 (s, 8H, CH2CH2); 3.10(m, J(H,H) = 6.9 Hz, 8H, CH); 1.40 (d, J(H,H) = 6.9 Hz, 24H, CH3); 1.26(d, J(H,H) = 6.9 Hz, 24H, CH3,);13C NMR (125.75 MHz, CD3CN, 25C,TMS): = 160.0 (N CH N); 147.2 (Ar); 131.0 (Ar); 125.5 (Ar); 53.7(CH2CH2); 28.5 (CH); 24.0 (CH3); 23.5 (CH3).

As the rapid development of chemical substances, we look forward to future research findings about 141556-45-8

Reference£º
Article; Silarska; Trzeciak; Pernak; Skrzypczak; Applied Catalysis A: General; vol. 466; (2013); p. 216 – 223;,
Chiral Catalysts
Chiral catalysts – SlideShare

141556-45-8, 1,3-Dimesityl-1H-imidazol-3-ium chloride is a chiral-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: A 20 mL vial was charged with the NHC¡¤HCl (300 mg, 1 equiv.) and the zinc salt (1 equiv.). Tetrahydrofuran (5 mL) was added, the vial was sealed with a screw-cap and the reaction was stirred at 60C for two hours. The mixture was allowed to reach room temperature and the solvent was removed under reduced pressure toafford the desired product., 141556-45-8

141556-45-8 1,3-Dimesityl-1H-imidazol-3-ium chloride 2734211, achiral-catalyst compound, is more and more widely used in various.

Reference£º
Article; Santoro, Orlando; Nahra, Fady; Cordes, David B.; Slawin, Alexandra M.Z.; Nolan, Steven P.; Cazin, Catherine S.J.; Journal of Molecular Catalysis A: Chemical; vol. 423; (2016); p. 85 – 91;,
Chiral Catalysts
Chiral catalysts – SlideShare

141556-45-8, 1,3-Dimesityl-1H-imidazol-3-ium chloride is a chiral-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: Ag2O (0.5 mmol) was added to a solution of the imidazolium ligand (1mmol) in CH2Cl2. The suspension became clear after stirring 3 h at room temperature. Then a solution of Me2SAuCl (1mmol) in CH2Cl2 was added dropwise. The reaction mixture was stirred for another 4 h. Then the solution was filtered through Celite and the solvent evaporated to leave a volume of ca. 3 ml. The addition of hexane led to the precipitation of a white solid., 141556-45-8

The synthetic route of 141556-45-8 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Perez-Galan, Patricia; Waldmann, Herbert; Kumar, Kamal; Tetrahedron; vol. 72; 26; (2016); p. 3647 – 3652;,
Chiral Catalysts
Chiral catalysts – SlideShare

The chiral-catalyst compound, cas is 141556-45-8 name is 1,3-Dimesityl-1H-imidazol-3-ium chloride, mainly used in chemical industry, its synthesis route is as follows.,141556-45-8

Tris [4- (pyridin-4-yl) phenyl] amine compound (47.6 mg, 0.10 mmol)1,3-bis (2,4,6-trimethylphenyl) imidazole chloride(IMes. HCl) (102.1 mg, 0.30 mmol),PdCl2 (53.2 mg, 0.30 mmol)And potassium carbonate (41.5 mg, 0.30 mmol) were added to a 25 mL single neck flask,Tetrahydrofuran (5 mL) was then added,The reaction was stirred at 75 C for 14 h under argon atmosphere.Stop the reaction,Cool to room temperature,concentrate,Thin layer chromatography to give compound II,Yield 50%.

As the rapid development of chemical substances, we look forward to future research findings about 141556-45-8

Reference£º
Patent; Shangqiu Normal University; Wang Tao; Xu Kai; Liu Lantao; Zhao Wenxian; Liu Shuang; Li Feng; Meng Tuanjie; Xie Huanping; (12 pag.)CN105131044; (2017); B;,
Chiral Catalysts
Chiral catalysts – SlideShare