A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, Safety of (2R,3R,4R,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 1772-03-8, Name is (2R,3R,4R,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride, molecular formula is C6H14ClNO5. In an article, author is Saito, Yuki,once mentioned of 1772-03-8.
Heterogeneous chiral Rh catalysts based on acid-base and electrostatic interactions have been developed. The robust catalysts demonstrate high activity and selectivity in the continuous-flow asymmetric hydrogenation of a wide variety of enamides and dehydroamino acids, providing optically active amides without leaching of metal species. The chiral environments can be easily tuned by changing the chiral ligands, demonstrating the high versatility of the heterogeneous catalysts. By applying these efficient catalysts, continuous synthesis of several active pharmaceutical ingredient intermediates was achieved.
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Reference:
Chiral Catalysts,
,Chiral catalysts – SlideShare