Category: 53152-69-5

In an article, published in an article, once mentioned the application of 53152-69-5, Name is (1R,2R)-N1,N1,N2,N2-Tetramethylcyclohexane-1,2-diamine,molecular formula is C10H22N2, is a conventional compound. this article was the specific content is as follows.Product Details of 53152-69-5

N,N-Dimethylferrocenylmethylamine can be lithiated stereoselectively by iPrLi in pentane/Et2O using catalytic amounts of the chiral auxiliary (R,R)-TMCDA. In homogenous reactions, high e.r. values were obtained upon crystallization of the lithiated species. The catalytic activity of TMCDA is made possible by its release from the stereomerically pure lithioferrocene as it dimerizes to a homochiral dimeric etherate. Copyright

Do you like my blog? If you like, you can also browse other articles about this kind. Product Details of 53152-69-5. Thanks for taking the time to read the blog about 53152-69-5

Reference：
Chiral Catalysts,
Chiral catalysts – SlideShare

In an article, published in an article, once mentioned the application of 53152-69-5, Name is (1R,2R)-N1,N1,N2,N2-Tetramethylcyclohexane-1,2-diamine,molecular formula is C10H22N2, is a conventional compound. this article was the specific content is as follows.COA of Formula: C10H22N2

Six alkali metal tris(HMDS) magnesiate complexes (HMDS, 1,1,1,3,3,3,-hexamethyldisilazide) containing chiral diamine ligands have been prepared and characterised in both the solid- and solution-state. Four of the complexes have a solvent-separated ion pair composition of the form [{M·(chiral diamine)2}+{Mg(HMDS)3} -] [M = Li for 1 and 3, Na for 2 and 4; chiral diamine = (-)-sparteine for 1 and 2, (R,R)-TMCDA for 3 and 4, (where (R,R)-TMCDA is N,N,N?,N?-(1R,2R)-tetramethylcyclohexane-1,2-diamine)] and two have a contacted ion pair composition of the form [{K·chiral diamine} +{Mg(HMDS)3}-]n [chiral diamine = (-)-sparteine for 5 and (R,R)-TMCDA for 6]. In the solid-state, complexes 1-4 are essentially isostructural, with the lithium or sodium cation sequestered by the respective chiral diamine and the previously reported anion consisting of three HMDS ligands coordinated to a magnesium centre. As such, complexes 1-4 are the first structurally characterised complexes in which the alkali metal is sequestered by two molecules of either of the chiral diamines (-)-sparteine (1 and 2) or (R,R)-TMCDA (3 and 4). In addition, complex 4 is a rare (R,R)-TMCDA adduct of sodium. In the solid state, complexes 5 and 6 exist as polymeric arrays of dimeric [{K·chiral diamine}+{Mg(HMDS) 3}-]2 subunits, with 5 adopting a two-dimensional net arrangement and 6 a linear arrangement. As such, complexes 5 and 6 appear to be the only structurally characterised complexes in which the chiral diamines (-)-sparteine (5) or (R,R)-TMCDA (6) have been incorporated within a polymeric framework. In addition, prior to this work, no (-)-sparteine or (R,R)-TMCDA adducts of potassium had been reported.

Do you like my blog? If you like, you can also browse other articles about this kind. COA of Formula: C10H22N2. Thanks for taking the time to read the blog about 53152-69-5

Reference：
Chiral Catalysts,
Chiral catalysts – SlideShare

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 53152-69-5, Name is (1R,2R)-N1,N1,N2,N2-Tetramethylcyclohexane-1,2-diamine, molecular formula is C10H22N2. In a Article，once mentioned of 53152-69-5, Formula: C10H22N2

Two closely related lithium alkylaluminium amides LiAl(TMP)2iBu2 and LiAl(TMP)iBu3 (TMP: 2,2,6,6-tetramethylpiperidide) have been compared in their reactivity towards six polydentate Lewis bases containing either N or O donor atoms or a mixed N,O donor set. Seven of the twelve potential organometallic products of these reactions, which were carried out in hexane solution, have been crystallographically characterised. Three of these structures, [Li(-Me2NCH2CHCH2CH2CHO)(-TMP)Al(iBu)2], [Li(-Me2NCH2CH2OCH2)(-TMP)Al(iBu)2], and [Li(-Me2NCH2CH2OCHCH2NMe2)(-TMP)Al(iBu)2] reveal that the bis-amide LiAl(TMP)2iBu2 deprotonates (aluminates) the multifunctional Lewis base selectively at the carbon atom adjacent to oxygen with the anion generated captured by the residue of the base. In contrast, the mono-amide LiAl(TMP)iBu3 in general fails to deprotonate the Lewis bases but instead forms co-complexes with them as evidenced by the molecular structures of [Me2NCH2CHCH2CH2CH2O·Li(-iBu)(-TMP)Al(iBu)2], [Me2NCH2CH2OMe·Li(- iBu)(-TMP)Al(iBu)2], and [MeOCH2CH2OMe·Li(-iBu)(-TMP)Al(iBu)2]. Providing an exception to this pattern, the mono-amide reagent deprotonates chiral R,R,-N,N,N?,N?-tetramethylcyclohexanediamine to afford [Li(-CH2NMeC6H10NMe2)2Al(iBu)2], the final complex to be crystallographically characterised. All new products have been spectroscopically characterised through 1H, 7 Li, and 13C NMR studies. Reaction mixtures have also been quenched with D2O and analysed by 2D NMR spectroscopy to ascertain the full metallation versus co-complexation picture taking place in solution.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data.Formula: C10H22N2, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 53152-69-5, in my other articles.

Reference：
Chiral Catalysts,
Chiral catalysts – SlideShare

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 53152-69-5, Name is (1R,2R)-N1,N1,N2,N2-Tetramethylcyclohexane-1,2-diamine, name: (1R,2R)-N1,N1,N2,N2-Tetramethylcyclohexane-1,2-diamine.

The chiral diamine (1R,2R)-N,N,N?,N?-tetramethylcyclohexane-1, 2-diamine [(R,R)-TMCDA, 3] has been selectively deprotonated at one of its methyl groups by a series of alkyllithium bases. Although the enantiomerically pure compound formed a trimeric structure, direct lithiation of the racemic mixture of the amine (trans-TMCDA) yielded a tetrameric compound. With 2 equiv. of the deprotonation reagent a mixed aggregate of the lithiated amine and tert-butyllithium was formed. The lithiated amine was employed as a building block for the synthesis of novel nitrogen ligands. The asymmetric 1,2-addition of alpha-lithiated (R,R)-TMCDA onto different ketones and aldehydes yielded a series of novel N,N,O ligands with different substitution patterns. Depending on the carbonyl compound used, a new stereocentre and different substituents can be introduced. The coordination behaviour of these ligands is illustrated by the formation of metal salt complexes. (R,R)-TMCDA and its racemic mixture can be directly deprotonated at its methyl group. With 2 equiv. of the deprotonation reagent a mixed aggregate 8 of the lithiated amine 7 and tBuLi was formed. By addition of alpha-lithiated (R,R)-TMCDA onto carbonyl compounds a series of novel N,N,O ligands of type 4 with different substituents and a further stereocentre are accessible.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.name: (1R,2R)-N1,N1,N2,N2-Tetramethylcyclohexane-1,2-diamine. In my other articles, you can also check out more blogs about 53152-69-5

Reference：
Chiral Catalysts,
Chiral catalysts – SlideShare

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.53152-69-5, Name is (1R,2R)-N1,N1,N2,N2-Tetramethylcyclohexane-1,2-diamine, molecular formula is C10H22N2. In a Article，once mentioned of 53152-69-5, Product Details of 53152-69-5

Enantioselective alkynylation of 1,5-dibromoanthracene-9,10-dione by alkynyllithium reagents prepared from alkynes, n-BuLi, and sparteine gave chiral cis-diols possessing two alkyne moieties with moderate ee. Subsequent Ru-catalyzed [2+2+2] cycloaddition of the diol with alkynes afforded chiral 1,5-dibromotriptycenes.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Product Details of 53152-69-5, you can also check out more blogs about53152-69-5

Reference：
Chiral Catalysts,
Chiral catalysts – SlideShare

Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, get their minds active, and encourage them to do something that doesn’t involve a screen. 53152-69-5, C10H22N2. A document type is Article, introducing its new discovery., SDS of cas: 53152-69-5

6Li and 13C NMR spectroscopic studies were carried out on [6Li]n-BuLi and [6Li]PhLi (RLi) in toluene-d8 containing the following diamines: N,N,N?,N?-tetramethylethylenediamine (TMEDA), N,N,N?,N?-tetraethyiethylenediamine, 1,2-dipyrrolidinoethane, 1,2-dipiperidinoethane, N,N,N?,N?-tetramethylpropanediamine, trans-(R,R)-N,N,N?,N?-tetramethylcyclohexanediamine, and (-)-sparteine. Dimers of general structure (RLi)2S2 (S = chelating diamine) are formed in each case. Treatment of RLi with two different diamines (S and S?) affords homosolvates (RLi)2S2 and (RLi)2S?2 along with a heterosolvate (RLi)2SS?. Relative binding constants and associated free energies for the sequential solvent substitutions are obtained by competing pairs of diamines. The high relative stabilities of certain heterosolvates indicate that solvent binding to the RLi dimer can be highly correlated. Rate studies of both the 1,2-addition of RLi/TMEDA to the N-isopropylimine of cyclohexane carboxaldehyde and the RLi/TMEDA-mediated alpha-lithiation of the N-isopropylimine of cyclohexanone reveal monomer-based transition structures, [(RLi)(TMEDA)(imine)]?, in all cases. The complex relationships of solvent binding constants and relative reactivities toward 1,2-additions and alpha-lithiations are discussed.

Interested yet? Keep reading other articles of 53152-69-5!, SDS of cas: 53152-69-5

Reference：
Chiral Catalysts,
Chiral catalysts – SlideShare

In an article, published in an article, once mentioned the application of 53152-69-5, Name is (1R,2R)-N1,N1,N2,N2-Tetramethylcyclohexane-1,2-diamine,molecular formula is C10H22N2, is a conventional compound. this article was the specific content is as follows.Product Details of 53152-69-5

Enantioselective addition of methyllithium to aromatic imines catalyzed by C2 symmetric tertiary diamines is described. Eleven diamines have been tested, for which dramatic effect of the nitrogen substitution has been observed. Diamines bearing hindered group close to the nitrogen led to racemic product while homologous hindered diamines led to the best results. Enantiomeric excess up to 74% could be achieved. An explanation of the absolute configuration of the product obtained is given considering the mechanism of the reaction.

Do you like my blog? If you like, you can also browse other articles about this kind. Product Details of 53152-69-5. Thanks for taking the time to read the blog about 53152-69-5

Reference：
Chiral Catalysts,
Chiral catalysts – SlideShare

Electric Literature of 53152-69-5, An article , which mentions 53152-69-5, molecular formula is C10H22N2. The compound – (1R,2R)-N1,N1,N2,N2-Tetramethylcyclohexane-1,2-diamine played an important role in people’s production and life.

The racemic alpha-phenylselanylalkyllithium compound 6 is monomeric in diethyl ether and forms diastereoisomeric complexes with a variety of chiral diamines.Diastereoisomer ratios were determined from 77Se NMR spectroscopy to lie around 60:40 for most examples, but reached 90:10 with N,N,N’,N’tetramethylcyclopentane-1,2-diamine (22).The complexation constants for the formation of the diastereoisomeric complexes 24a and 24b formed from 6 with the latter ligand were estimated by NMR titration to be > 800 dm3 mol-1 and > 90 dm3 mol-1.The diastereoisomeric complexes 24 epimerize at the lithium bearing stereocentre with a barrier of DeltaG(excit.) = 12.1 +/-0.3 kcal mol-1 at -4 deg C.As this epimerization process is not slower than the racemization of the uncomplexed alkyllithium compound 6, the complexes 24 equilibrate directly and do not have to dissociate into 6 in order to equilibrate.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 53152-69-5, help many people in the next few years., Electric Literature of 53152-69-5

Reference：
Chiral Catalysts,
Chiral catalysts – SlideShare

Electric Literature of 53152-69-5. Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 53152-69-5, Name is (1R,2R)-N1,N1,N2,N2-Tetramethylcyclohexane-1,2-diamine

A series of pentacoordinate d8 PtII complexes, of the type [PtCl2(eta2-CH2=CH2)(MenNN)], where MenNN = bis-nitrogen ligand, with a variable number of Me groups (i.e., 2,2?-bipyridyl; 1,10-phenanthroline; 6-methyl-2,2?-bipyridyl; 2,9-dimethyl-1,10-phenanthroline; 2,9-dimethyl-1,10-phenanthroline; N,N?-trimethyl-ethylenediamine; N,N,N?,N?-tetramethyl-ethylenediamine; N,N,N?,N?-tetramethyl-1,2-diaminocyclohexane) was studied. The compounds are characterized by variable steric hindrance, due to the variable number (n) of Me substituents, on or ortho to the N-donors of aliphatic diamines or aromatic diimines, respectively. This approach was developed to investigate the interaction of substituents with the metal coordination sphere. With this aim, we analyzed the NMR properties of the considered complexes, with respect to modulation of the metal electron density (195Pt NMR signal frequency) by alkyl groups close to the N-donors. 1H and 13C NMR analysis of the eta2-olefin signals has revealed, for each kind of bis-nitrogen ligand, a positive or negative chemical shift variation that is proportional to the number of Me groups geminal or vicinal to the N-donors. Interestingly, the 1JPt,C values increase by approximately 45 Hz for each additional Me on the series of diamine or diimine bis-nitrogen ligands. A rationale for the stability changes observed in such pentacoordinate complexes is suggested, based on the NMR spectroscopic data analysis. The effect of steric hindrance around bis-nitrogen donors on the metal-olefin bond, according to the Dewar-Chatt-Ducanson model, is described. Low hindrance around bis-nitrogen donors corresponds to a weaker metal-olefin interaction, whereas high steric hindrance around bis-nitrogen donors corresponds to a stronger metal-olefin interaction.

If you are hungry for even more, make sure to check my other article about 53152-69-5. Electric Literature of 53152-69-5

Reference：
Chiral Catalysts,
Chiral catalysts – SlideShare

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.53152-69-5, Name is (1R,2R)-N1,N1,N2,N2-Tetramethylcyclohexane-1,2-diamine, molecular formula is C10H22N2. In a Article，once mentioned of 53152-69-5, category: chiral-catalyst

The four-electron reduction of dioxygen to water by trinuclear copper clusters is of great biological significance. Recently we reported the crystal structure of a trinuclear model complex in which the three coppers provide the four electrons necessary to fully reduce dioxygen, generating two mu3-oxo bridges. This complex is best described as a localized, mixed- valence Cu(II,II,III) system which has C(2v) effective symmetry. The magnetic properties of this trincular cluster have been investigated by MCD and SQUID magnetic susceptibility. The two Cu(II) ions are found to be ferromagnetically coupled with a triplet/singlet splitting of 14 cm-1. Density functional calculations reproduce these geometric, electronic, and magnetic properties of the trinuclear cluster and provide insight into their origin. Since the trinuclear copper complex has a 3+ charge, the Cu3O2 core is one electron too oxidized to permit each atom to be in a preferred oxidation state (2+ for Cu and 2- for O). The extra hole in this highly oxidized Cu3O2 cluster is found to be localized on one Cu, which is therefore a Cu(III) ion, rather than on an O ligand (which would then be an oxyl) due to the strong stabilization of the oxo valence orbitals which derives from bridging to the Cu(II) centers. The communication between the coppers is weak, as it involves superexchange through the oxo bridges which provide nearly orthogonal orbital pathways between the copper ions. This leads to a ferromagnetic interaction between the two Cu(II) ions and weak electronic coupling between the Cu(III) and the Cu(II) ions. In the idealized D(3h) high; symmetry limit which would be the favored geometry in the case of complete electronic delocalization, the triplet ground state is orbitally degenerative and subject to a large Jahn-Teller distortion [E’ direct product e’] toward the observed C(2v) structure. This combination of a large Jahn- Teller distortion and weak electronic coupling leads to localization of the Cu(III) on one metal center.

The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 53152-69-5 is helpful to your research., category: chiral-catalyst

Reference：
Chiral Catalysts,
Chiral catalysts – SlideShare