Application of 21436-03-3, Chemistry can be defined as the study of matter and the changes it undergoes. You¡¯ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology.21436-03-3, Name is (1S,2S)-Cyclohexane-1,2-diamine, molecular formula is C6H14N2. In a patent, introducing its new discovery.
Highly enantioselective Michael addition of alpha,alpha-disubstituted aldehydes to maleimides catalyzed by new primary amine-squaramide bifunctional organocatalysts
New bifunctional primary amine-squaramides catalyzed asymmetric Michael addition reaction of alpha,alpha-disubstituted aldehydes to maleimides has been developed. This organocatalytic asymmetric reaction provides easy access to functionalized succinimides with a broad substrate scope. Both enantiomers of desired succinimide derivatives were obtained in good to excellent yields (up to 98%) with excellent enantioselectivities (up to >99% ee).
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Reference£º
Chiral Catalysts,
Chiral catalysts – SlideShare