Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 67579-81-1, Name is trans-N1,N2-Dimethylcyclohexane-1,2-diamine, molecular formula is C8H18N2, belongs to chiral-catalyst compound. In a document, author is Kim, Byungjun, introduce the new discover, Recommanded Product: 67579-81-1.
We report here a stereodivergent method for the Michael addition of aryl acetic acid esters to alpha,beta-unsaturated aldehydes catalyzed by a combination of a chiral pyrrolidine and a chiral Lewis base. This reaction proceeds through a synergistic catalytic cycle which consists of one cycle leading to a chiral iminium electrophile and a second cycle generating a nucleophilic chiral enolate for the construction of a carbon-carbon bond. By varying the combinations of catalyst enantiomers, all four stereoisomers of the products with two vicinal stereocenters are accessible with high enantio- and diastereoselectivity. The products of the Michael addition, 1,5-aldehyde esters, can be readily transformed into a variety of other valuable enantioenriched structures, including those bearing three contiguous stereocenters in an acyclic system, thus providing an efficient route to an array of structural and stereochemical diversity.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 67579-81-1. Recommanded Product: 67579-81-1.
Reference:
Chiral Catalysts,
,Chiral catalysts – SlideShare