As a common heterocyclic compound, it belongs to quinuclidine compound,Quinuclidine-4-carboxylic acid hydrochloride,40117-63-3,Molecular formula: C8H14ClNO423,mainly used in chemical industry, its synthesis route is as follows.,141556-45-8
General procedure: 0.340 g (1.00 mmol) of 1,3-bis(2,4,6-trimethylphenyl)imidazolium chloride was deprotonated by the addition of n-BuLi (1.00 mmol) in THF at -40C. The reaction mixture was allowed to stir for 30 min after which 0.390 g dimanganese decacarbonyl (1.00 mmol) was added. The reaction mixture turned a deep orange colour after the introduction of the metal complex and the reaction mixture was allowed to slowly warm up to room temperature. The solvent was removed in vacuo and purified via silica gel chromatography by eluting first with hexane and secondly with a hexane-DCM 1:1 mixture.
With the synthetic route has been constantly updated, we look forward to future research findings about 1,3-Dimesityl-1H-imidazol-3-ium chloride,belong chiral-catalyst compound
Reference£º
Article; Fraser, Roan; van Sittert, Cornelia G.C.E.; van Rooyen, Petrus H.; Landman, Marile; Journal of Organometallic Chemistry; vol. 835; (2017); p. 60 – 69;,
Chiral Catalysts
Chiral catalysts – SlideShare