351498-10-7, 6,6′-((1E,1’E)-((2,3-Dimethylbutane-2,3-diyl)bis(azanylylidene))bis(methanylylidene))bis(2,4-di-tert-butylphenol) is a chiral-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
EXAMPLE 1Preparation of Intermediate Compound Int-lclnt-1a n – c Compound Int-la (733 mg, 1.33 mmol) was suspended in ethanol (10 mL) and the resulting suspension was heated to 80 C and allowed to stir for 5 minutes. Compound Int- lb (236 mg, 1.33 mmol) was then added and the resulting reaction was allowed to stir at 80 C for an additional 2 hours. The reaction was then cooled to room temperature using in an ice bath and the reaction mixture was filtered. The collected red solid was dried under vacuum to provide compound Int-lc (579 mg, 72%).
The synthetic route of 351498-10-7 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; MERCK SHARP & DOHME CORP.; GIRIJAVALLABHAN, Vinay; NJOROGE, F. George; BOGEN, Stephane; VERMA, Vishal; BENNETT, Frank; KEREKES, Angela; ARASAPPAN, Ashok; PISSARNITSKI, Dmitri; DANG, Qun; DAVIES, Ian; OLSEN, David, B.; STAMFORD, Andrew; VACCA, Joseph, P.; WO2012/142085; (2012); A1;,
Chiral Catalysts
Chiral catalysts – SlideShare