673-06-3, D-Phenylalanine is a chiral-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
673-06-3, EXAMPLE A (R)-2-Bromo-3-phenylpropanoic Acid Sodium nitrite (27 g in water) is added at 0C to a solution of D-phenylalanine (40 g) in a mixture of 48% hydrobromic acid/water (1:1 by volume). The mixture is stirred for 30 minutes at 0C and then for 2 hours 30 minutes at a temperature close to 20C. The reaction mixture is extracted with ether. The organic extracts are washed with water and then with a saturated sodium chloride solution and then dried over sodium sulphate. After filtration and concentration to dryness, the obtained residue is purified by distillation. (R)-2-Bromo-3-phenylpropanoic acid (33 g) is obtained which has the following characteristics: B.p.1 kPa= 154C; Rf= 0.47 (methylene chloride/methanol). The yield is 60%.
The synthetic route of 673-06-3 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; INSTITUT NATIONAL DE LA SANTE ET DE LA, RECHERCHE MEDICALE (INSERM); EP524553; (1993); A1;,
Chiral Catalysts
Chiral catalysts – SlideShare