673-06-3, D-Phenylalanine is a chiral-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a stirred solution of D-Phenylalanine (15 g, 90.80 mmol, 1 equiv.) in 5% aqueous NaHCO3 (800 mL)at room temperature was added benzyl chloroformate (15.34 mL, 108.97 mmol, 1.2 equiv.) and resultingmixture was allowed to stir for 12 h. Diethyl ether (200 mL) was added to remove the excess of benzylchloroformate. Aqueous layer was acidified with 6 N hydrochloric acid to pH 1 and extracted with ethylacetate (300 mL ¡Á 3). Combined organic layers were dried with anhydrous MgSO4, filtered andconcentrated under reduced pressure to give compound 11 (27 g) as a white solid in quantitative yield.The product was directly used for next step without any further purification., 673-06-3
The synthetic route of 673-06-3 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Wan, Yang; Stanovych, Andrii; Gori, Didier; Zirah, Severine; Kouklovsky, Cyrille; Alezra, Valerie; European Journal of Medicinal Chemistry; vol. 149; (2018); p. 122 – 128;,
Chiral Catalysts
Chiral catalysts – SlideShare