The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. Safety of (R)-Methyl 2-hydroxypropanoate, 17392-83-5, Name is (R)-Methyl 2-hydroxypropanoate, SMILES is C[C@@H](O)C(OC)=O, in an article , author is Nakao, Ryota, once mentioned of 17392-83-5.
C-1-Symmetric chiral ammonium salt catalysts induced a kinetic resolution of racemic alpha-nitrolactones through an asymmetric ester-amide exchange reaction. The corresponding amides were obtained with high enantioselectivities and high S(=k(fast)/k(slow)) values. This reaction system is a useful approach for obtaining carbocyclic quaternary alpha-nitroamides as chiral building blocks.
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Reference:
Chiral Catalysts,
,Chiral catalysts – SlideShare