So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Moll, Annette; Hubner, Harald; Gmeiner, Peter; Troschutz, Reinhard researched the compound: Ethyl 5-chloro-3-formyl-1H-indole-2-carboxylate( cas:43142-76-3 ).Recommanded Product: 43142-76-3.They published the article 《Phenylpiperazinylmethylindolecarboxylates and derivatives as selective D4-Ligands》 about this compound( cas:43142-76-3 ) in Bioorganic & Medicinal Chemistry. Keywords: phenylpiperazinylmethylindolecarboxylate derivative preparation structure activity dopamine D4 receptor binding. We’ll tell you more about this compound (cas:43142-76-3).
Novel phenylpiperazinylmethylindolecarboxylates were synthesized for evaluation as potential D4-ligands. Test compounds showed high affinity for the human dopamine D4 receptor and great selectivity over the other receptor subtypes. Intrinsic effects of indole derivatives, which indicated most promising binding properties, were investigated in a mitogenesis assay.
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