145-42-6, Name is Monosodium taurocholate, molecular formula is C26H44NNaO7S, Formula: C26H44NNaO7S, belongs to chiral-catalyst compound, is a common compound. In a patnet, author is Qiu, Haile, once mentioned the new application about 145-42-6.
The synthesis ofP-stereogenic building blocks is extremely difficult. Herein we report an efficient kinetic resolution of secondary phosphine oxidesviaa Le-Phos-catalyzed asymmetric allylation reaction with Morita-Baylis-Hillman carbonates. This method provides facile access to enantioenriched secondary and tertiaryP-chiral phosphine oxides with broad substrate scope, both of which could serve asP-stereogenic synthons, and can be rapidly incorporated into a given scaffold bearing aP-stereocenter. The highly desirable late stage modifications demonstrate the practicability of our method and can be a critical contribution to obtaining optimalP-chiral catalysts and ligands.
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 145-42-6 help many people in the next few years. Formula: C26H44NNaO7S.
Reference:
Chiral Catalysts,
,Chiral catalysts – SlideShare