141-22-0, Name is (R,Z)-12-Hydroxyoctadec-9-enoic acid, molecular formula is C18H34O3, belongs to chiral-catalyst compound, is a common compound. In a patnet, author is Chang, Yejin, once mentioned the new application about 141-22-0, Computed Properties of C18H34O3.
We disclose a catalytic method for beta-C(sp(3))-H functionalization of N-alkylamines for the synthesis of enantiomerically enriched beta-substituted amines, entities prevalent in pharmaceutical compounds and used to generate different families of chiral catalysts. We demonstrate that a catalyst system comprising of seemingly competitive Lewis acids, B(C6F5)(3), and a chiral Mg- or Sc-based complex, promotes the highly enantioselective union of N-alkylamines and alpha,beta-unsaturated compounds. An array of delta-amino carbonyl compounds was synthesized under redox-neutral conditions by enantioselective reaction of a N-alkylamine-derived enamine and an electrophile activated by the chiral Lewis acid co-catalyst. The utility of the approach is highlighted by late-stage beta-C-H functionalization of bioactive amines. Investigations in regard to the mechanistic nuances of the catalytic processes are described.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 141-22-0. The above is the message from the blog manager. Computed Properties of C18H34O3.
Reference:
Chiral Catalysts,
,Chiral catalysts – SlideShare