Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. In an article, author is Jiang, Zhiwei, once mentioned the application of 67579-81-1, Name is trans-N1,N2-Dimethylcyclohexane-1,2-diamine, molecular formula is C8H18N2, molecular weight is 142.2419, MDL number is MFCD03001702, category is chiral-catalyst. Now introduce a scientific discovery about this category, Computed Properties of C8H18N2.
An efficient and flexible synthesis of a new class of chiral bifunctional NHC catalyst has been reported. These new imidazolylidene NHCs, bearing a (thio)urea function as a hydrogen bond donor promoted efficiently highly diastereoselective trans-cyclopentannulation of enals and enones in moderate to good yields (up to 69 % yield) along with excellent enantioselectivity (up to 96 % ee). This methodology could be applied to a large variety of substrates (30 examples).
Do you like my blog? If you like, you can also browse other articles about this kind. Thanks for taking the time to read the blog about 67579-81-1, Computed Properties of C8H18N2.
Reference:
Chiral Catalysts,
,Chiral catalysts – SlideShare