Introduction of a new synthetic route about 1121-22-8

With the rapid development of chemical substances, we look forward to future research findings about 1121-22-8

trans-Cyclohexane-1,2-diamine, cas is 1121-22-8, it is a common heterocyclic compound, the chiral-catalyst compound, its synthesis route is as follows.,1121-22-8

First, 5.84g of benzyl (manufactured by Tokyo Kasei Kogyo Co., Ltd) was mixed with 3.17g of trans- 1,2-cyclohexanediamine (manufactured by Kanto Kagaku) by using 150 mL of ethanol as a solvent. Then, the mixed solution was refluxed for 3 hours at 500C. After that, the refluxed solution was cooled to be a room temperature. A deposit was obtained by filtering the refluxed solution. After that, 2,3-diphenyl-4a,5,6,7,8,8a-hexahydroquinoxaline was obtained by recrystallizing the deposit with ethanol (light yellow crystal, yield: 96%). Subsequently, 7.66g of 2,3-diphenyl-4a,5,6,7,8,8a-hexahydroquinoxaline, which was obtained in the above step, was mixed with 8.62g of iron chloride (III) by using 80 mL of ethanol as a solvent. Then the mixed solution was gently stirred with heat for 3 hours. After the stirring, a ligand 2,3-diphenyl-5,6,7,8-tetrahydroquinoxaline (abbreviation: DPQtH) was obtained by adding water (milky white powder, tield: 88%).

With the rapid development of chemical substances, we look forward to future research findings about 1121-22-8

Reference£º
Patent; SEMICONDUCTOR ENERGY LABORATORY CO., LTD.; WO2006/104177; (2006); A1;,
Chiral Catalysts
Chiral catalysts – SlideShare