HPLC of Formula: 542-58-5. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: 2-Chloroethyl acetate, is researched, Molecular C4H7ClO2, CAS is 542-58-5, about Double ester prodrugs of FR900098 display enhanced in-vitro antimalarial activity. Author is Wiesner, Jochen; Ortmann, Regina; Jomaa, Hassan; Schlitzer, Martin.
Fosmidomycin and FR900098 are inhibitors of the 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR; IspC), a key enzyme of the mevalonate-independent isoprenoid biosynthesis pathway. The authors have determined the in-vitro antimalarial activity of two double ester prodrugs (I)and (II) in direct comparison with the unmodified FR900098 against intraerythrocytic forms of Plasmodium falciparum. Temporarily masking the polar properties of the phosphonate moiety of the DXR inhibitor FR900098 I enhanced not only its oral bioavailability but also the intrinsic activity of this series against the parasites.
As far as I know, this compound(542-58-5)HPLC of Formula: 542-58-5 can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.