One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, such as the rate of change in the concentration of reactants or products with time. 87-69-4, Name is (2R,3R)-2,3-Dihydroxysuccinic acid, formurla is C4H6O6. In a document, author is Murai, Takuya, introducing its new discovery. Safety of (2R,3R)-2,3-Dihydroxysuccinic acid.
D-2-symmetric dirhodium(II) carboxylate catalysts that bear axially chiral binaphthothiophene delta-amino acid derivatives have been developed. Conformational control is supported through chalcogen-bonding interactions between sulfur and oxygen atoms in each ligand, providing well-defined and uniform asymmetric environments around the catalytically active Rh(II) centers. These structural properties make such complexes asymmetric catalysts for the stereoselective intramolecular C-H insertion into alpha-aryl-alpha-diazoacetates to yield a variety of cis-alpha,beta-diaryl gamma-lactones, as well as the corresponding trans-isomers through epimerization, in high diastereo- and enantioselectivities. Short total syntheses of the naturally occurring gamma-lactones, cinnamomumolide, cinncassin A(7), and cinnamomulactone were also accomplished using this conformationally controlled catalyst.
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Reference:
Chiral Catalysts,
,Chiral catalysts – SlideShare