With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.7181-87-5,1,3-Dimethyl-1H-benzo[d]imidazol-3-ium iodide,as a common compound, the synthetic route is as follows.
General procedure: Weigh accurately 2eq bis(pinacolato)diboron, 2.5eq sodium carbonate and 0.2mmol 2- nitrochalcone was added to the pressure reactor tube containing 3mL of ethanol, after being charged with nitrogen was stirred in an oil bath at 100 of reaction 12h after treatment as in Example 1, with petroleum ether: ethyl acetate = 50: 1 eluent, the product yield of 78%.
The synthetic route of 7181-87-5 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Huaqiao University; Song, Quiling; Yang, Kai; (7 pag.)CN105669517; (2016); A;,
Chiral Catalysts
Chiral catalysts – SlideShare