Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: Ethyl 5-chloro-3-formyl-1H-indole-2-carboxylate, is researched, Molecular C12H10ClNO3, CAS is 43142-76-3, about Synthesis of 11H-1,2,4-triazolo[4,3-b]pyridazino[4,5-b]indoles.Computed Properties of C12H10ClNO3.
4-Oxo-5H-pyridazino[4,5-b]indoles, obtained from the corresponding 3-formylindole-2-carboxylates, were subjected to chlorination to obtain the corresponding 4-chloro-5H-pyridazino[4,5-b]indoles which on reaction with hydrazine hydrate in the presence of K2CO3 give 4-hydrazino-5H-pyridazino[4,5-b]indole. The latter were treated with acetic acid/benzoyl chloride to yield the desired title compounds I (R = Me, OMe, Br, OEt, Cl; R1 = Me, Ph). These compounds were screened for their antimicrobial activity.
In some applications, this compound(43142-76-3)Computed Properties of C12H10ClNO3 is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.