So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Martinetz, Dieter researched the compound: 2-Chloroethyl acetate( cas:542-58-5 ).Application of 542-58-5.They published the article 《Detoxification of aliphatic dihalogen compounds via solid-liquid phase transfer-catalyzed formation of diacetates》 about this compound( cas:542-58-5 ) in Zeitschrift fuer Chemie. Keywords: detoxification dihaloalkane; haloalkane di detoxification; glycol diacetate; diol alkane diacetate. We’ll tell you more about this compound (cas:542-58-5).
BrCH2CH2Br (LD50 140 mg/kg, orally, rat) was detoxified by refluxing 6 h with PhCH2Bu3N+Cl- and KOAc in MeCN to give ∼90% AcOCH2CH2OAc (LD50 6850 μg/kg, orally, rat) and ∼10% BrCH2CH2OAc. ClCH2CH2Cl (LD50 140 mg/kg) was detoxified similarly in 12 h, but the MeCN was omitted, to give ∼80% AcOCH2CH2OAc and ∼20% ClCH2CH2OAc. Br(CH2)4Br and Br(CH2)6Br with KOAc and PhCH2Bu3N+ Cl- in 5 h gave 98% AcO(CH2)4OAc and 96% AcO(CH2)6OAc, resp.
As far as I know, this compound(542-58-5)Application of 542-58-5 can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.